IBL/Anti-Mouse C-ERC/Mesothelin (308) Rabbit IgG/JP28127/
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3392242852
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4000-520-616
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商品介绍
| Quantity/Tests | 50µg |
| Species/Antigen | mouse |
| Host | rabbit |
| Subclass/Clone | IgG |
| Type | Polyclonal |
| Purification | withAntigenPeptide |
| Label | No |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Anti-MouseC-ERC/Mesothelin(308)RabbitIgG
ERChasbeenidentifiedasageneshowingstrongerexpressionincancer-affectedrenaltissuethaninnormalrenaltissueinEkerrats(aratmodelofrenalcancer).ThehumanhomologueoftheproteinencodedbythisgeneiscalledMPF(megakaryocytepotentiatingfactor)ormesothelin.Thisproteinisdetectedprominentlyinmesothelialcells,andithasbeensuggestedbeinginvolvedinthedevelopmentofmesothelioma,makingitapromisingtumorMarker.Inhumans,involvementofthisproteinhasalsobeensuggestedinthedevelopmentofpancreatic,ovarianandpulmonarycancers,etc.TheproteinisexpressedasaGPIanchor-typemembraneousprotein(about71kDainmolecularweight),whichisthoughttobecleavedbyafurin-likeproteasetoyieldfragmentsabout31kDaofN-terminalsideandabout40kDaofC-terminalside.WethinkitishelpfulforresearchofERC/Mesothelinproteinandhavecharacterizedthe31kDafragmentasN-ERC/Mesothelinandthe40kDafragmentasC-ERC/Mesothelin.
ThisantibodyisrecognizesmouseC-ERC/Mesothelin.
DistributedbyIBLInternational
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.ThisantibodyisrecognizesmouseC-ERC/Mesothelin.
DistributedbyIBLInternational
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