IBL/抗小鼠ALK（mAb 16-39）大鼠IgG-MoAb/JP10373/
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联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Quantity/Tests | 100μg |
| Species/Antigen | RecombinantproteinoftheextracellulardomainofmouseALK |
| Host | Rat |
| Subclass/Clone | IgG2b/mAb16-39 |
| Type | Monoclonal |
| Purification | AffinitypurifiedwithProteinG |
| Label | No |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Anti-MouseALK(mAb16-39)RatIgGMoAb
Anaplasticlymphomakinase(ALK,anaplasticlymphomakinase)isareceptortypetyrosinekinase,andisfoundtobeexpressedinthecentralandperipheralnervoussystematlateembryonicstage.Motegietal.developedanagoNISTmonoclonalantibodyagainsttheextracellulardomainofALK.
Thismonoclonalantibody(clonemAb16-39)elicitstyrosinephosphorylationofALKinhumanneuroblastoma(SK-N-SH)cells.ItalsoinducesfurtherphosphorylationofsignaltransfermoleculeslikeIRD-1(insulinreceptorsubstrate-1)whichinteractswithALK.Moreover,continuousincubationwiththisantibodyinducedthecell-growthandneuriteoutgrowthofSK-N-SHcells.
DistributedbyIBLInternational
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Thismonoclonalantibody(clonemAb16-39)elicitstyrosinephosphorylationofALKinhumanneuroblastoma(SK-N-SH)cells.ItalsoinducesfurtherphosphorylationofsignaltransfermoleculeslikeIRD-1(insulinreceptorsubstrate-1)whichinteractswithALK.Moreover,continuousincubationwiththisantibodyinducedthecell-growthandneuriteoutgrowthofSK-N-SHcells.
DistributedbyIBLInternational
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