| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x1h,1x30min,1x15min |
| Standardrange | cut-offindex |
| Specimen/Volumes | 10µLserum,plasma |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Trichinosis(alsocalledtrichinellosis)iscausedbynematodes(roundworms)ofthegenusTrichinella.InadditiontotheclassicalagentTrichinellaspiralis,whichisfoundworldwideinmanycarnivorousandomnivorousanimals,fourotherspecies(T.pseudospiralis,T.nativa,T.nelsoni,andT.britovi)arerecognized.TrichinosisisacquiredbyingestingmeatcontainingcystsofTrichinella.Afterexposuretogastricacidandpepsin,thelarvaearereleasedfromthecystsandinvadethesmallbowelmucosawheretheydevelopintoadultworms(female2.2mminlength,males1.2mm).After1week,thefemalesreleaselarvaethatmigratetothestriatedmuscleswheretheyencyst.Encystmentiscompletedin4to5weeksandtheencystedlarvaemayremainviableforseveralyears.Ingestionoftheencystedlarvaeperpetuatesthecycle.Trichinosisinfectionoccursworldwide,butismostcommoninpartsofEuropeandtheUnitedStates.Lightinfectionsmaybeasymptomatic.Formildtomoderateinfections,mostsymptomssubsidewithinafewmonthswhereasfatigue,weakness,anddiarrhoeamaylastformonths.Inseverecases,deathcanoccur.Infectionmaybeidentifiedby
- Microscopy,musclebiopsy
- SEROlogy:DetectionofantibodiesbyELISA
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