| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x1h,1x30min,1x15min |
| Standardrange | cut-offindex |
| Specimen/Volumes | 10µLserum |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Toxocaracanis(anascarid)isaparasiticnematode(roundworm)commonlyfoundintheintestineofdogs.Humansareparatenichostswhobecomeinfectedbyingestinginfectiveeggsincontaminatedsoil.Afteringestion,theeggsyieldlarvaethatpenetratetheintestinalwallandarecarriedbythecirculationtoawidevarietyoftissues(liver,heart,lungs,brain,muscle,eyes).Whilethelarvaedonotundergoanyfurtherdevelopmentinthesesites,theycancauseseverallocalreactionsthatarethebasisoftoxocariasis.Inmostcases,Toxocarainfectionsarenotserious,andmanypeople,especiallyadultsinfectedbyasmallnumberoflarvae(immatureworms),maynotnoticeanysymptoms.Themostseverecasesarerare,butaremorelikelytooccurinyoungchildren,whooftenplayindirt,oreatdirtcontaminatedbydogstool.ThetwomainclinicalpresentationsoftoxocariasisareOcularLarvaMigrans(OLM),aneyediseasethatcancauseblindness(eachyearmorethan700peopleinfectedwithToxocaraexperiencepermanentpartiallossofvision),andVisceralLarvaMigrans(VLM),adiseasethatcausesswellingofancillarybody’sorgansorcentralnervoussystem.Thepresenceofparasiteresp.infectionmaybeidentifiedby
- Microscopy
- SEROlogy:DetectionofantibodiesbyELISA
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