IBL/Anti-human Daple Rabbit IgG/30112280/
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¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Quantity/Tests | 100µg |
| Species/Antigen | SyntheticpeptideofDaple(EPGGDPQTVWYEYG) |
| Host | Rabbit |
| Subclass/Clone | IgG |
| Type | Polyclonal |
| Purification | AntigenPeptide |
| Label | No |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Anti-humanDapleRabbitIgG
"Originalarticle#28147Thecanonical(β-catenindependent)andnon-canonical(β-cateninnon-dependent)Wntsignalingpathwaysaresignalpathwaysthatregulateformationandmaintainanceofembryonicgrowthorcellstructuresoforgansandamplificationofcells.Itisalsoinvolvedinvariousdiseasesincludingcancers.Ithasbeenwellknownthatthenon-canonicalWntsignalingpathwayregulatespolaritydeterminationoftissuesandmigrationofcells.Ithasbeenrevealedthatthescaffoldmolecules“Dishevelled(Dvl)”andlowmolecularweightGTPase“Rhomoleculargroup(Rac,Rho)”haveessentialrolesinthispathway.
DapleisamoleculethatwasidentifiedbyA.Kikuchietal,OsakaUniversityandtheyshowedthatithasahomologoussequencewithGirdinorGipie.ItissuggestedthatDaplebindstoDvlandcontrolsactivationofRacdependendonWnt5astimulusviaitsmutualinteraction.ItwasdiscoveredthatDapleisessentialforcellmigrationandrestructuringofactinstructureanditsmolecularmechanismhasalsoanimportantroleforhealingofwoundofskinbyDapleknockoutmouseanalysis."
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.DapleisamoleculethatwasidentifiedbyA.Kikuchietal,OsakaUniversityandtheyshowedthatithasahomologoussequencewithGirdinorGipie.ItissuggestedthatDaplebindstoDvlandcontrolsactivationofRacdependendonWnt5astimulusviaitsmutualinteraction.ItwasdiscoveredthatDapleisessentialforcellmigrationandrestructuringofactinstructureanditsmolecularmechanismhasalsoanimportantroleforhealingofwoundofskinbyDapleknockoutmouseanalysis."
品牌介绍
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