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当前位置: 首页 > 产品中心 > globulin > IBL/Anti-human Daple Rabbit IgG/30112280/
商品详细IBL/Anti-human Daple Rabbit IgG/30112280/
IBL/Anti-human Daple Rabbit IgG/30112280/
IBL/Anti-human Daple Rabbit IgG/30112280/
商品编号: 30112280
品牌: TECAN
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 球蛋白
公司分类: globulin
联系Q Q: 3392242852
电话号码: 4000-520-616
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商品介绍
Quantity/Tests100µg
Species/AntigenSyntheticpeptideofDaple(EPGGDPQTVWYEYG)
HostRabbit
Subclass/CloneIgG
TypePolyclonal
PurificationAntigenPeptide
LabelNo
RegulatoryStatus:Forresearchuseonly
Detailsfor: Anti-humanDapleRabbitIgG
"Originalarticle#28147Thecanonical(β-catenindependent)andnon-canonical(β-cateninnon-dependent)Wntsignalingpathwaysaresignalpathwaysthatregulateformationandmaintainanceofembryonicgrowthorcellstructuresoforgansandamplificationofcells.Itisalsoinvolvedinvariousdiseasesincludingcancers.Ithasbeenwellknownthatthenon-canonicalWntsignalingpathwayregulatespolaritydeterminationoftissuesandmigrationofcells.Ithasbeenrevealedthatthescaffoldmolecules“Dishevelled(Dvl)”andlowmolecularweightGTPase“Rhomoleculargroup(Rac,Rho)”haveessentialrolesinthispathway.

DapleisamoleculethatwasidentifiedbyA.Kikuchietal,OsakaUniversityandtheyshowedthatithasahomologoussequencewithGirdinorGipie.ItissuggestedthatDaplebindstoDvlandcontrolsactivationofRacdependendonWnt5astimulusviaitsmutualinteraction.ItwasdiscoveredthatDapleisessentialforcellmigrationandrestructuringofactinstructureanditsmolecularmechanismhasalsoanimportantroleforhealingofwoundofskinbyDapleknockoutmouseanalysis."
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
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