IBL/U1 RNP抗体ELISA/RE75211/
市场价:
¥4140.00
美元价:
2484.00
产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 3x30min |
Standardrange | 0-60U/mL,cut-off4U/mL |
Specimen/Volumes | 5µLserum |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | EU:CE |
Detailsfor: U1-RNP-AbELISA
EnzymeimmunoassayforthequalitativeandquantitativedeterminationofIgGantibodiesagainstU1-RNPinhumanserum.Uracil-rich,smallnuclearRNAs(U-snRNA)arephysiologicallycomplexedwithproteinstoribonucleoproteinparticles(U-snRNP)whichareinvolvedinthesplicingprocessofpre-mRNA.Differentcomplexes(U1-U6)canbedistinguishedaccordingtotheparticipatingRNA;theirproteincomponentsareinpartcommon,inpartdifferent.Forexample,U1-snRNAiscomplexedwiththeso-calledSm-proteinswhicharealsopresentinotherU-snRNPs,andwiththeU1-specificproteinsA,Cand68kDa.AutoantibodiesdirectedagainstthesethreeU1-specificproteinsareconsideredasdiagnosticMarkerformixedconnectivetissuedisease(MCTD).Theyarealsoassociatedwithsystemiclupuserythematosus(SLE)butoccurwithdistinctlylowerprevalence(about35%)andmostlyincombinationwithfurtherantinuclearantibodies(ANA).Nowadays,proteinsA,Cand68kDaareregardedastheactualRNPantigen,ratherthanthecompleteU1-RNP.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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