IBL/VEGF受体1 ELISA/BE59131/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x20min |
| Standardrange | 0.16-10ng/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:VEGF-Receptor1ELISA
SolubleVEGF-R1(sFLT-1)isanaturallyoccurringendogenousformoftheVEGF-R1andwasoriginallyfoundinthesupernatantofhumanvascularendothelialcells.InvitrosVEGF-R1isusedtoinhibitVEGF-Amediatedsignalsinendothelialcellsandinvivoitcanbeusedtoblockphysiologicalangiogenesisinseveralorgans,e.g.intheovaryorinbones.Characterizationofangiogenicactivity,suchasembryonicdevelopment,placentalvascularization,cancerandwoundhealingismeasuredbycomparingtheratioofangiogenicstimulators(e.g.FGF-2,FGF-1,VEGF-A,Ang-1)toangiogenicinhibitors(e.g.sFLT-1,angiostatin,endostatin,thrombospondin).SeveralindependentlypublisheddataofbothnormalandpathogenicsubjectshaveconfirmedendogenouslevelsofVEGF-AandbFGFinpg/mlranges.Thesefactorshavebeenthoughttoworkunopposedtocausebloodvesselformation.ThefindingthatsVEGF-R1,astrongVEGF-AantagoNIST,ispresentinnormalsubjectssuggestsafinelytunedbalanceofsignaltransduction,theworkingsofwhichcannowbeexplored.Togetherwithothersimilarassaysystems,positiveandnegativeangiogenicregulatorscannowbeexploredinmanydifferentphysiologicalandpathologicalsettingsusinghumancellculturesupernatantsandBIOLOGicalsfluids.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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