IBL/抗人C4.4A（301）兔IgG/JP28073/
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Quantity/Tests | 50µg |
| Species/Antigen | human |
| Host | rabbit |
| Subclass/Clone | IgG |
| Type | Polyclonal |
| Purification | withAntigenPeptide |
| Label | No |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Anti-HumanC4.4A(301)RabbitIgG
C4.4Aisknowntobepresentintheplacenta,skin,esophagusandperipheralmononuclearcellsinhumans.ItisaGPI(glycosylphosphatidylinositol)bindingproteinwhichhasasimilarstructuretourokinasereceptor(uPAR)andbelongstotheLy-6familyofproteinsasdoesuPAR.WhilemostofLy-6familyproteinsconsistofsingledomains,uPARisofthreecysteine-richdomains.C4.4AisamembraneproteinwhichbindstocellmembraneatGPIbindingsite,andisconsistingoftwocysteine-richdomainsandacysteinelackingthirddomain.
C4.4Awasfirstisolatedfrommetastaticratpancreaticcancercelllinesin1989,anditshumanhomologwasisolatedin2001.Inhumanmalignanttumors,ithasbeenreportedthatC4.4Aisexpressedinmalignantmelanoma,urothelial,lung,esophagealandcoloncancer.ItisconsideredthatC4.4AmediatesinvasionandmetastasisofcancercellsbybindingwithlamininanddegrADIngtheextracellularmatrixintheprogressofcancer.
Therefore,immunologicaldetectionofC4.4Aincanceroustissueisexpectedtobeanindicatoroftumormetastasis.
DistributedbyIBLInternational
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.C4.4Awasfirstisolatedfrommetastaticratpancreaticcancercelllinesin1989,anditshumanhomologwasisolatedin2001.Inhumanmalignanttumors,ithasbeenreportedthatC4.4Aisexpressedinmalignantmelanoma,urothelial,lung,esophagealandcoloncancer.ItisconsideredthatC4.4AmediatesinvasionandmetastasisofcancercellsbybindingwithlamininanddegrADIngtheextracellularmatrixintheprogressofcancer.
Therefore,immunologicaldetectionofC4.4Aincanceroustissueisexpectedtobeanindicatoroftumormetastasis.
DistributedbyIBLInternational
品牌介绍
IBL我们的愿景是通过Tecan技术，产品和支持，为世界各地的每个实验室提供支持。我们旨在通过无与伦比的专业知识，产品和客户支持来塑造生命科学和临床诊断自动化工作流程的未来。
