IBL/Anti-Human Angiotensinogen (104AT 6012.80) Mouse IgG/JP10417/
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3392242852
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4000-520-616
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商品介绍
| Quantity/Tests | 100µg |
| Species/Antigen | Recombinantproteinofhumanangiotensinogen |
| Host | Mouse |
| Subclass/Clone | IgG1/104AT601.2.80 |
| Type | No |
| Purification | AffinitypurifiedwithProteinA |
| Label | No |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Anti-HumanAngiotensinogen(104AT6012.80)MouseIgG
AngiotensinogenistheprecursorofangiotensinandiscleavedintoangiotensinIandIIintherenin-angiotensinsystem,andithaslongbeenreportedtoplayanimportantroleincontrollingbloodpressure.Inrecentyearsinterestrelatedtotheroleoftherenin-angiotensinsysteminarterialpressurecontrolandthepathophysiologyofhypertensionhasbeenshiftingtoitslocalroleinvarioustissues.AmongthestudiesurinaryexcretionofangiotensinogeninaratmodelofangiotensinII(AII)-dependenthypertensionhasbeenreportedtobeaMarkeroftheactivityofthelocalintrarenalrenin-angiotensinsystem.IntrarenalAIIincreasestoanextentinAII-dependenthypertensionthatcannotbeexplainedbytheplasmaAIIequilibrationalone,andtwomechanisms,anincreaseinintracellularuptakeofAIIandanincreaseinintrarenalexpressionofangiotensinogen,havebeenproposedtoexplainit.
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ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.DistributedbyIBLInternational
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