IBL/Vitamin B12/Folat RIA/BD19101/
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商品介绍
Kitsize | 100 |
Method | RIA(Potein) |
Incubationtime | 1x15min,2x10min,1x1h |
Standardrange | 100-2000pg/mLB12;1-20ng/mLFolate |
Specimen/Volumes | 200µLserum,plasma |
Substrate/isotope | 57Co<55kBq;125I<110kBq |
RegulatoryStatus: | EU:CE |
Detailsfor: VitaminB12/FolatRIA
VitaminB12andfolatedeficienciesaretwoofthethreeunequivocalnutritionalanemiasofman,thethirdbeingthatduetolackofiron.Folate(folicacid)deficiencyispresentinaboutone-thirdofallpregnantwomen,thevastmajorityofalcoholics,themajorityofpeoplewhoeatadietdevoidofrawfruitsandvegetablesorfreshfruitjuices,manypeoplewithstructuralorfunctionaldamageintheupperthirdofthesmallbowelandinanumberofothersituations.Measurementoffolatelevelsconstitutesadirectandreliablemeansofdeterminingtheexistenceoffolatedeficiency,andthistestshouldbeperformedforeverypatientwhohasamegaloblasticanemia,aswellaseverypatientwhohasanemia,hypersegmentationofthegranulocyticnuclei,andcoincidentevidenceofirondeficiency.VitaminB12isessentialfornormalfolicacidmetabolism.ItisadvisabletodetermineserumvitaminB12andredcellfolateinadditiontoserumfolatetoascertainthatthediagnosisisfolatedeficiency,forwhichthepropertreatmentisfolicacid.AlowredcellfolatecanalsomeanthatthepatienthasprimaryvitaminB12deficiency,blockingtheABIlityofcellstotakeupfolate,inwhichcasethepropertherapywouldbevitaminB12ratherthanfolicacid.VitaminB12deficiencyismostfrequentlyassociatedwithperniciousanemia,gastricdamage,intestinaldamageandpurevegetarianism.TheonlysignificantdietarysourcesofvitaminB12areofanimalorigin
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