IBL/PSA ELISA/CA51081/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x1h,1x30min |
Standardrange | 1-60µg/L |
Specimen/Volumes | 25µLserum |
Substrate/isotope | TMB405/620nm |
RegulatoryStatus: | EU:CE |
Detailsfor: PSAELISA
PSAisa32kDasinglechainglycoproteinserineproteasewithachymotrypsinlikespecificityproducedbythesecretoryepitheliumoftheprostategland.PSAisnormallysecretedintotheseminalfluidandplaysafunctionalroleinthecleavageoftheseminalvesicleproteinsandtheliquefactionoftheseminalcoagulum.OnlylowlevelsofPSAarenormallypresentinthebloodstream,andincreasingserumconcentrationsindicateprostaticpathology,includingbenignprostatichyperplasiaandcanceroftheprostate.DeterminationofPSAisnowwidelyusedfordetectionandmanagementofpatientswithprostaticcancerandconsideredasthesuperiorSEROlogicalMarkerforcanceroftheprostate(3,8).PSAhasbeenshowntoformstablecomplexeswithdifferentantiproteasesandthedominatingportionofPSAinpatientserumoccursincomplexwitha1-antichymotrypsin(PSA-ACT)(4).HowevertherearelargevariationsintherelationbetweenfreePSAandPSA-ACTcomplexbetweendifferentindividuals.StudieshavealsoindicatedthattheproportionoffreePSAishigherinbenignprostaticdiseaseascomparedtoprostaticcancer(5).TheantibodiesintheCanAgPSAEIAhavebeencarefullyevaluatedandselectedtogivethesamemolarresponseforfreePSAasforthePSA-ACTcomplex(7).TheCanAgPSAEIAthusgivesatrue“total”PSAvalueindependentoftheindividualvariationsoffreeandACT-complexedPSA.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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