IBL/组织蛋白酶-L ELISA/BE59211/
市场价：
¥10020.00
美元价：
6012.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x10min. |
| Standardrange | 3.12-50ng/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Cathepsin-LELISA
CathepsinLiscloselyrelatedtotherecentlydescribedcathepsinV(L2)andthesequenceindentityofalmost80%betweenthemrequiresantibodiesforthedetectionofcathepsinLwhichdonotcrossreactwithcathepsinV.ThisrequirementcanonlybemetbyepitopespecificmonoclonalantibodiesasareusedinBE59211.
CathepsinLisalysosomalcysteineproteinaseconsistingofaheavychainofabout25kDaandalightchainofabout5kDaderivedproteolyticallyfromthesameprecursor.CathepsinLhasbeenshowntobeproducedbymanydifferentcelltypes.SincecathepsinLiscapableofdegrADIngproteinconstituentsoftheextracellularmatrixitisassumedtoplayacrucialroleintumorprogressionandmetastasisandanumberofotherdisorderswherethedestructionoftheextracellularmatrixisthemajorcauseofdisease(e.g.rheumatoidarthritis,neurodegeneration).Synonyms:Majorexcretedprotein,MEP,CathepsinLprecursor
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.CathepsinLisalysosomalcysteineproteinaseconsistingofaheavychainofabout25kDaandalightchainofabout5kDaderivedproteolyticallyfromthesameprecursor.CathepsinLhasbeenshowntobeproducedbymanydifferentcelltypes.SincecathepsinLiscapableofdegrADIngproteinconstituentsoftheextracellularmatrixitisassumedtoplayacrucialroleintumorprogressionandmetastasisandanumberofotherdisorderswherethedestructionoftheextracellularmatrixisthemajorcauseofdisease(e.g.rheumatoidarthritis,neurodegeneration).Synonyms:Majorexcretedprotein,MEP,CathepsinLprecursor
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