IBL/SLA Ab ELISA/RE70791/
市场价：
¥7000.00
美元价：
4200.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 3x30min |
| Standardrange | 0-300U/ml;cut-off15U/ml |
| Specimen/Volumes | 10µLserum |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:SLA-AbELISA
SLA-AbELISAisasolidphaseenzymeimmunoassayemployinghumanrecombinantSLA/LPforthequantitativeandqualitativedetectionofantibodiesagainstsolubleliverantigen(SLA)inhumanserum.Theassayisatoolforthediagnosisofautoimmunehepatitis(AIH).Autoimmunehepatitis(AIH)isachronicprogressiveliverdiseaseofunknownoriginthatrespondswelltoimmunosuppressivetherapy,buthasapoorprognosisifuntreated.Earlyandaccuratediagnosisisthereforeofgreatimportance.AIHischaracterizedbyhistologicalfeaturesofperiportalhepatitisintheabsenseofviralMarkers,byhypergammaglobulinemiaand,inthemajorityofpatients,bythepresencesmooth-muscleautoantibodies(SMA)orliver-kidneymicrosomalautoantibodies(LKM).Theseantiofpatientswithviralhepatitisandotherimmune-mediateddiseases.Incontrast,antibodiestosolubleautoimmunehepatitisandarepresentin20%ofallAIH-patients,manyofwhomarenegativeforotherautoantibodies.Itwasshownthatanti-SLAandanti-LParedirectedagainstthesameantigenandthusareidentical.TheSLA/LPantigenclonedandsequencedin2000isaproteinofunknownfunction,suggestedtobeanUGA-suppressortRNA-associatedprotein.ANA/SMAandanti-SLApositivepatientssharemostclinical,biochemical,histologicalandprognosticfeatures.Distinctionofdifferentsubgroupsaccordingtoautoantibodystatusisthereforeclinicallynothelpful.However,testingforanti-SLAautoantibodiesisveryimportantforthediagnosisofAIHinmanypatientswhoarenegativeforotherautoantibodiesandmayotherwisebemisdiagnosed.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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