IBL/PR3抗体（c-ANCA）ELISA/RE75611/
市场价：
¥4140.00
美元价：
2484.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 3x30min |
| Standardrange | 0-100U/mL,cut-off8U/mL |
| Specimen/Volumes | 5µLserum |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Detailsfor:PR3-Ab(c-ANCA)ELISA
EnzymeimmunoassayforthequalitativeandquantitativedeterminationofIgGantibodiesagainstproteinase3(PR3)inhumanserum.Anti-neutrophilcytoplasmicantibodies(ANCA),originallyidentifiedbyimmunofluorescenceassays(IFA),aredirectedagainstcytoplasmiccomponentsofneutrophilgranulocytesandmonocytes.TheyhaveproventobeausefulSEROlogicMarkerforanumberofsystemic,autoimmunemediatedvasculitides.Agranularcytoplasmatic(c-ANCA)stainingpatternoftheneutrophilsubstrateisindicativeforautoantibodiesagainstproteinase3(PR3),a29kDaserineproteinasepresentintheazurophilicgranulesofhumangranulocytesandmonocytes.PR3antibodiesoccurinpatientswithWegener"sgranulomatosis(WG),asystemicvasculitisaffectingtherespiratorytract.Theirspecificityisabout95%,theirsensitivitydependsonthephaseandactivityofthedisease.ThetiteroftheseantibodiesreflectsthecourseofWGandprovidesatooltocontrolthetherapyefficiency.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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