IBL/Cardiolipin IgG/IgM ELISA/RE70521/
市场价：
¥5220.00
美元价：
3132.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 3x30min |
| Standardrange | 0-300GPL/mL,0-300MPL/mL,cut-off15GPL/mL,cut-off15MPL/mL |
| Specimen/Volumes | 10µLserum |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Detailsfor:CardiolipinIgG/IgMELISA
Cardiolipin-AbIgG/IgMELISAisasolidphaseenzymeimmunoassayemployinghighlypurifiedcardiolipinplusnativehumanß2-glycoproteinIforthequantitativedetectionofIgGandIgMantibodiesagainstcardiolipininhumanserum.Anti-cardiolipinantibodiesmainlyrecognizespecificepitopesonacomplexcomposedofcardiolipinandß2-glycoproteinIwhichareonlyexpressedwhenß2-glycoproteinIinteractswithcardiolipin.Theassayisanaidinthediagnosisandriskestimationofthrombosisinpatientswithsystemiclupuserythematosus(SLE).Antibodiesagainstcardiolipinbelongtothegroupofanti-phospholipidantibodiesspecificfornegativelychargedphospholipids,componentsofBIOLOGicalmembranes.Cardiolipinisanacidicphospholipidderivedfromglycerolandwasnamendbecauseofitsisolationfrombovineheartin1941.Anti-phospholipidantibodiesarefrequentlyfoundinseraofpatientswithsystemiclupuserythematosus(SLE)andrelateddiseases.Theprevalenceofanti-cardiolipinantibodiesinSLEis24-50%.Theoccurrenceofanti-cardiolipinantibodiesinpatientswithSLEandrelateddiseasesistypicalforasecondaryanti-phospholipidsyndrome(APS).Incontrast,anti-cardiolipinantibodiesinpatientswithnootherautoimmunediseasescharacterizetheprimaryanti-phospholipidsyndrome(APS).Manystudieshaveshownacorrelationbetweentheseautoantibodiesandanenhancedincidenceofthrombosis,thrombocytopeniaandhABItualabortions(asaconsequenceofplacentalinfarct).Theexactmechanismbywhichpathogenicanti-phospholipidantibodiesinducethrombosisisnotyetrevealedfully.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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