IBL/Interleukin-4 (IL-4) ELISA/BE53041/
市场价：
¥0.00
美元价：
0.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x10min |
| Standardrange | 7.8-500pg/mL |
| Specimen/Volumes | 50µLserum,plasma,urine,cellculturesupernatant |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Detailsfor:Interleukin-4(IL-4)ELISA
HumanIL-4existinmolecularweightformsbetween15and19kDa,representingvariableglycosylation.ThegeneforhumanIL-4isfoundonthelongarmofchromsome5incloseassociationwithgenesforIL-13,IL-5GM-CSFandIL-3.IL-4mediatesitsfunctionbybindingtoreceptorsexpressedontargetcells.ReceptorsexistonfreshlypreparedBandTlymphocytesandmacrophages,aswellasonvariouscelllinesincludinglymphoidcells,mastcelllines,avarietyofotherhematopoieticcelllines,fibroblastsandstromalcelllines.OnTandBcells,receptorsarepresentinlownumbers(appr.400),whicharereportedtobeup-regulatedbyIL-2andIL-4.IL-4isproducedbyaparticularsubsetofThelpercells,theTH2cells.ThesecellstendtomakeaspecificsetoflymphokinesincludingIL-4,IL-5,IL-6,IL-10,IL-13,IL-3andGM-CSFandfailtoproduceIL-2,IFNgamma,andlymphotoxin(TNFbeta).ApartfromTcells,ithasbeenshownthatmastcellscanproduceIL-4.IL-4exertsnumerouseffectsonvarioushematopoieticcelltypes.OnBcells,IL-4promotesimmunologicalclassswitchingtoIgEandIgG1isotypesandupregulatesMHCclassIIandCD23expression.Itcanpromotesurvival,growth,anddifferentiationofbothTandBlymphocytes,mastcells,andendothelialcells.Inaddition,IL-4caninhibittheproductionofTNF,IL-1,andIL-6bymacrophages.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
IBL我们的愿景是通过Tecan技术，产品和支持，为世界各地的每个实验室提供支持。我们旨在通过无与伦比的专业知识，产品和客户支持来塑造生命科学和临床诊断自动化工作流程的未来。
