IBL/IL-23（IL-23）ELISA/BE53231/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x30min.,1x15min. |
| Standardrange | 15.6-2000pg/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatant |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Interleukin-23(IL-23)ELISA
Interleukin-23wasfoundduringagenomescanfortheIL-6/IL-12cytokinefamily.IL-23proteinisaheterodimer,sharingap40subunitwithIL-12,buthavingadistinctp19subunit,whichisIL-23specific.IL-23usesmanyofthesamesignal-transductioncomponentsasIL-12,soitbindstoIL-12Rβ1receptor,butnotIL-12Rβ2.IL-23playsaroleintype1-polarizedT-cellimmuneresponses.AlthoughIL-12stronglyactivatesnaïveT-cells,theinitialdescriptionofIL-23reportedpreferentialactionsonmemoryT-cellstoincreaseIFNγproductionandproliferationsuggestinganimportantroleforIL-23incontrollingbacterialinfections.IL-23hasfurtherbeendescribedasakeycytokinecontrollinginflammationinperipheraltissues.Overexpressionofp19correlateswithinflammationinmultipleorgansandepithelialtissuesincludingskin.IL-23wasshowntobeinvolvedininflammationofthenervoussystemandautoimmunediseases.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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