IBL/IL-13（IL-13）ELISA/BE53131/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x10min |
| Standardrange | 1.6-100pg/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Detailsfor:Interleukin-13(IL-13)ELISA
HumanIL-13isanonglycosylatedproteinof132aminoacidswithamolecularweightof12kDa.IL-13isapleiotropiccytokinewhosespectrumofactionencompassesBcells,mononuclearphagocytes,andlargegranularlymphocytes.IL-13inducesCD23expressiononBcells,promotesBcellproliferationincombinationwithanti-IgorCD40antibodies,andstimulatessecretionIgE,andIgG4.IL-13hasalsobeenshowntoprolongsurvivalofhumanmonocytesandincreasessurfaceexpressionofMHCclassII,CD23,andmembersoftheintegrinsuperfamily,likeCD11b,CD11c,CD18,CD29andCD49e.IL-13inhibitstheproductionofaseriesofcytokineslikeIL-1,IL-6,TNF-alpha,andIL-8byactivatedhumanmonocytes.IL-13inducesIFN-gammaproductionbyNKcells.ThecapacityofIL-13toinduceIgEsynthesisindicatesthatIL-13mayplayanimportantregulatoryroleinIgE-mediatedatopicdiseases.ThemeasurementofIL-13inbodyfluidsmaythusprovidefurtherinformationaboutthepathophysiologyofatopicdiseases.FurThermore,IL-13inhibitsHIV-1replicationinprimaryculture-derivedmacrophagesandrepresentsacandidatecytokineforthesuppressionofHIVinfectionwithinmonocytesandmacrophagesinvivo.
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