IBL/IL-12p70（IL-12p70）高灵敏度ELISA/BE58121/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x15min,1x30min,1x10-20min |
| Standardrange | 0.16-10pg/ml |
| Specimen/Volumes | 50µlserum,plasma,cellculturesupernatant |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Interleukin-12p70(IL-12p70)HighSensitivityELISA
ThisHighSensitivityELISAenablestheanalysisofInterleukin-12p70inlowconcentrationsfromserum,plasma,orcellculturesamples.TheHighSensitivityELISAKitsofferaccuratequantificationbelowconventionalELISAlimits.ThisismadepossIBLebytheirinherentdesignbyamplifyingthesignal.
ThebioactiveformofIL-12isa75kDaheterodimer(IL12p70)comprisedofindependently-regulateddisulfide-linked40kDa(p40)and35kDa(p35)subunits.Thep40subunitcanalsoformahomodimerwhichhasbeenshowntobeabletobindtheIL-12receptorandthusactsasanIL-12antagoNIST.Additionally,thep40subunithasbeenfoundtobeexpressedinahighexcessoverp70.IL-12exertsavarietyofBIOLOGicaleffectsonhumanTandnaturalkillercells.ApartfrompromotionofTh1developmentanditsABIlitytopromotecytolyticactivityitmediatessomeofitsphysiologicalactivitiesbyactingasapotentinducerofinterferon(IFN)gammaproductionandthestimulationofothercytokinesfromperipheralbloodTandNKcells.
Synonyms:Cytotoxiclymphocytematurationfactor,CLMF,NKcellstimulatoryfactor,NKSF1
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.ThebioactiveformofIL-12isa75kDaheterodimer(IL12p70)comprisedofindependently-regulateddisulfide-linked40kDa(p40)and35kDa(p35)subunits.Thep40subunitcanalsoformahomodimerwhichhasbeenshowntobeabletobindtheIL-12receptorandthusactsasanIL-12antagoNIST.Additionally,thep40subunithasbeenfoundtobeexpressedinahighexcessoverp70.IL-12exertsavarietyofBIOLOGicaleffectsonhumanTandnaturalkillercells.ApartfrompromotionofTh1developmentanditsABIlitytopromotecytolyticactivityitmediatessomeofitsphysiologicalactivitiesbyactingasapotentinducerofinterferon(IFN)gammaproductionandthestimulationofothercytokinesfromperipheralbloodTandNKcells.
Synonyms:Cytotoxiclymphocytematurationfactor,CLMF,NKcellstimulatoryfactor,NKSF1
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