IBL/小鼠N-ERC/间皮素ELISA/JP27783/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x1h,2x30min |
| Standardrange | 0.5-32ng/mL |
| Specimen/Volumes | 100µLserum,EDTA-plasma,cellculturesupernatant |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:MouseN-ERC/MesothelinELISA
ERChasbeenidentifiedasageneshowingstrongerexpressionincancer-affectedrenaltissuethaninnormalrenaltissueinEkerrats(aratmodelofrenalcancer).ThehumanhomologueoftheproteinencodedbythisgeneiscalledMPF(megakaryocytepotentiatingfactor)ormesothelin.Thisproteinisdetectedprominentlyinmesothelialcells,andithasbeensuggestedtobeinvolvedinthedevelopmentofmesothelioma,makingitapromisingtumorMarker.Inhumans,involvementofthisproteinhasalsobeensuggestedinthedevelopmentofpancreatic,ovarianandpulmonarycancers,etc.TheproteinisexpressedasaGPIanchor-typemembraneprotein(about71kDainmolecularweight),thatisthoughttobedigestedbyafurin-likeproteasetoyieldfragmentsofabout31kDaand40kDainsize.Wecallthe31kDaproteinN-ERC/Mesothelin.InliteraturethenomenclatureisMPF(MegakaryocytePotentiatingFactor).The40kDafragmentiscalledC-ERC/MesothelinorjustcleavedMesothelin
ThisELISAkitcanmeasureMouseN-ERC/Mesothelin.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.ThisELISAkitcanmeasureMouseN-ERC/Mesothelin.
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