IBL/Cytomegalovirus (CMV) IgM ELISA/RE58321/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x60min18-25°C;1x30min18-25°C;1x20min18-25°C |
| Standardrange | 0-120U/mL;Cut-off10U/mL |
| Specimen/Volumes | 5µLSerum,Plasma |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Detailsfor:Cytomegalovirus(CMV)IgMELISA
Cytomegalyiscausedbyaviralinfection,whichshowsaninapparentprogression,howeverleadstoserioussymptomswithimmune-compromisedpatientsandnewborns.
Thecytomegalyvirus(CMV)withaparticlediameterof100nm(inclusiveenvelopethevirionmeasures200nm)belongstothefamilyofherpesviridaelikeHerpes1andHerpes2.Thetransmissioniseffectedviasalivaandbylong-termintimatecontacts.Theincubationtimeis2-10daysforprimaryinfections.
CytomegalyappearsoftenduringthegrAvidity,andperyearupto5%ofthepregnantwomenshowclinicalsignsofthedisease.Intheearlyphasetheillnessfrequentlyremainsundetected,andtheaffectedwomenthemselvesshownosymptoms.Whenhowevernewbornsareinfected(1%ofthebirths),theseshowin10%ofthecasesdiseasesymptomswithlatedamageslikeretinitis,ulceraofthemucousmembrane,viralpneumonia,meningitis,microencephaly,hydrocephalusandskinulcerations.Theincidenceofwomencapableofchildbearingisestimatedtobe65%,sothatanassessmentoftheimmunestatusbeforepregnancyismandatory.Afteranegativeresult,acontrolcheckisrecommendedinthe20thweekofgestation.
BesidesthesymptomatictreatmentaspecifictherapywithphosphonoformateandganciclovirispossIBLe.Avaccinationdoesnotexist,sothatinthecaseofaninfectiononlypassiveCMVimmunoglobulinsareadmiNISTered.
Togetherwiththedifferentialassessmentoftheabovementionedsymptoms,thediagnosisisperformedclinicallyintissuesamplesviatheso-called“owleyes”.Thefollowinglaboratorymethodsareavailable:CFandELISA,determinationofvirusnucleicacid(PCR)aswellasvirusisolation(cellculture).SEROlogically,IgGandIgMantibodiescanbedetectedandquantitatedbytheELISAtechnique.AlsothemeasurementoftheavidityoftheIgGmoleculesisappropriate.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Thecytomegalyvirus(CMV)withaparticlediameterof100nm(inclusiveenvelopethevirionmeasures200nm)belongstothefamilyofherpesviridaelikeHerpes1andHerpes2.Thetransmissioniseffectedviasalivaandbylong-termintimatecontacts.Theincubationtimeis2-10daysforprimaryinfections.
CytomegalyappearsoftenduringthegrAvidity,andperyearupto5%ofthepregnantwomenshowclinicalsignsofthedisease.Intheearlyphasetheillnessfrequentlyremainsundetected,andtheaffectedwomenthemselvesshownosymptoms.Whenhowevernewbornsareinfected(1%ofthebirths),theseshowin10%ofthecasesdiseasesymptomswithlatedamageslikeretinitis,ulceraofthemucousmembrane,viralpneumonia,meningitis,microencephaly,hydrocephalusandskinulcerations.Theincidenceofwomencapableofchildbearingisestimatedtobe65%,sothatanassessmentoftheimmunestatusbeforepregnancyismandatory.Afteranegativeresult,acontrolcheckisrecommendedinthe20thweekofgestation.
BesidesthesymptomatictreatmentaspecifictherapywithphosphonoformateandganciclovirispossIBLe.Avaccinationdoesnotexist,sothatinthecaseofaninfectiononlypassiveCMVimmunoglobulinsareadmiNISTered.
Togetherwiththedifferentialassessmentoftheabovementionedsymptoms,thediagnosisisperformedclinicallyintissuesamplesviatheso-called“owleyes”.Thefollowinglaboratorymethodsareavailable:CFandELISA,determinationofvirusnucleicacid(PCR)aswellasvirusisolation(cellculture).SEROlogically,IgGandIgMantibodiescanbedetectedandquantitatedbytheELISAtechnique.AlsothemeasurementoftheavidityoftheIgGmoleculesisappropriate.
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