| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x1h,2x30min |
| Standardrange | cut-offindex |
| Specimen/Volumes | 10µLserum |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Cytomegalovirus(CMV)isamemberoftheherpesvirusgroup(Betasubfamily,DNAvirusof150-200nm).ThesevirusesshareacharacteristicABIlitytoremaindormantwithinthebodyoveralongperiod.InitialCMVinfection,whichmayhavefewsymptoms,isalwaysfollowedbyaprolonged,inapparentinfectionduringwhichthevirusresidesincellswithoutcausingdetectabledamageorclinicalillness.Severeimpairmantofthebody´simmunesystembymedicationordiseaseconsistentlyreactivatesthevirusfromthelatentordormantstate.CMVisfounduniversallythroughoutallgeographiclocationsandsocioeconomicgroups,andinfectsbetween50%and85%ofadults.CMVinfectionismorewidespreadindevelopingcountriesandinareasoflowersocioeconomicconditions.Forthevastmajorityofpeople,CMVinfectionisnotaseriousproblem,butitistocertainhigh-riskgroups:
- theunbornbabyduringpregnancy
- peoplewhoworkwithchildren
- immunocompromisedpersons,suchasorgantransplantrecipientsandpersonsinfectedwithHIV
Thepresenceofvirusresp.infectionmaybeidentifiedby
- Microscopy
- PCR
- SEROlogy:CBR,DetectionofantibodiesbyELISA
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