| Kitsize | 96 |
| Method | ELISA |
| Incubationtime | 1x1h,1x30min,1x15min |
| Standardrange | cut-offIndex |
| Specimen/Volumes | 10µlSerum |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Chlamydiaearenomotile,Gramnegativeandobligatoryintracellulargrowingbacteriawhichformcharacteristicinclusionswithinthecytoplasmofparasitizedcells.TheyareeasilyvisIBLeinthelightmicroscope.ThreedifferentChlamydiaspeciespathogenicforhumansareknown:Chlamydiatrachomatis,ChlamydiapneumoniaeandChlamydiapsittaci,andonespeciesonlypathogenicforanimals(C.pecorum).Chlamydiatrachomatisisthemostprevalentagentofsexuallytransmitteddiseasesworldwide(400-500millioncases)andthenumberofinfectionsisconstantlygrowing.PregnantwomeninfectedwithC.trachomatismaytransmitthesebacteriaduringchildbirth,causingconjunctivitisorpneumoniainnewborns.Untreatedcasesofchlamydialinfectioncanleadtochronicsalpingitis,possiblyresultinginectopicpregnancyorinfertility.Inmales,C.trachomatisisamajorcauseofnon-gonococcalurethritis.AsevereprobleminChlamydiainfectionsisthefrequentasymptomaticinsidiouscoursewhichmayresultintheinitiationofchronicdiseases.Inmanyinstancesprimaryinfectionsarenotrecognizedandonlythesequelaecausedbyascended,persistingagentsarediagnosed.Infectionmaybeidentifiedby
- Microscopy:Giemsastain
- PCR
- SEROlogy:DetectionofantigensbyELISAordetectionofantibodiesbyIF,EIA,ELISA
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