IBL/Chikungunya IgG capture ELISA/RE58831/
市场价:
¥10820.00
美元价:
6492.00
产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x1h,3x30min,1x15min |
Standardrange | cut-offindex |
Specimen/Volumes | 10µlserum |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | EU:CE |
Detailsfor: ChikungunyaIgGcaptureELISA
ChikungunyavirusisanarthropodbornevirusofthegenusAlphavirus(familyTogaviridae).TheAlphavirusgenuscontainsatleast24distinctspecies.Thesearelipid-envelopedvirionswithadiameterof50to60nm.
Alphavirusinfectionsareinitiatedbythebiteofaninfectedmosquito,whichresultsinthedepositionofvirusinsubcutaneousandpossIBLycutaneoustissues.Afteranincubationperiodof1to12daystheChikungunyafeverdevelops.
Chikungunyafever(Chikungunyameans“thatwhichbendsup”,inreferencetothecripplingmanifestationsofthedisease)isanacuteviralinfectioncharacterizedbyarapidtransitionfromastateofgoodhealthtoillnessthatincludesseverearthralgiaandfever.
Temperaturerisesabruptlytoashighas40°Candisoftenaccompaniedbyshakingchills.Afterafewdays,fevermayabateandrecrudesce,givingrisetoa“saddleback”fevercurve.Arthralgiaispolyarticular,favoringthesmalljointsandsitesofpreviousinjuries,andismostintenseonarising.Patientstypicallyavoidmovementasmuchaspossible.Jointsmayswellwithoutsignificantfluidaccumulations.Thesesymptomsmaylastfrom1weektoseveralmonthsandareaccompaniedbymyalgia.Therashcharacteristicallyappearsonthefirstdayofillness,butonsetmaybedelayed.Itusuallyarisesasaflushoverthefaceandneck,whichevolvestoamaculopapularormacularformthatmaybepruritic.Thelatterlesionsappearonthetrunk,limbs,face,plamsandsoles,inthatorderoffrequency.Petechialskinlesionshavealsobeennoted.Headache,photophobia,retro-orbitralpain,sorethroatwithobjectivesignsofpharyngitis,nauseaandvomitingalsooccurinthissetting.Occasionally,howeverpersistentarthralgiaandpolyarthritis(lastingmonthsorevenyears)dooccur,sometimesinvolvingjointdestruction.Evenrarer,sequelaeincludeencephalitisandmeningoencephalitiswithhighlethalityrates.
ThevirushasmajorimportanceinAfricaandAsia.From20%tomorethan90%ofthepopulationoftropicalandsubtropicalshowSEROlogicevidenceofinfection.BecauseAedesmosquitoesareincreasinglyprevalentinNorthAfricaandSouthAmerica,wherethepopulationwouldbeuniformlysusceptibletoinfection,thepossibilityforepidemicsisevident.ChikungunyavirusinfectionsareimportedtocentralEuropemainlybytravellerstotropicalandsubtropicalcountries.
Thepresenceofvirusresp.infectionmaybeidentifiedby
•Serology:DetectionofantibodiesbyIF,ELISA
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Alphavirusinfectionsareinitiatedbythebiteofaninfectedmosquito,whichresultsinthedepositionofvirusinsubcutaneousandpossIBLycutaneoustissues.Afteranincubationperiodof1to12daystheChikungunyafeverdevelops.
Chikungunyafever(Chikungunyameans“thatwhichbendsup”,inreferencetothecripplingmanifestationsofthedisease)isanacuteviralinfectioncharacterizedbyarapidtransitionfromastateofgoodhealthtoillnessthatincludesseverearthralgiaandfever.
Temperaturerisesabruptlytoashighas40°Candisoftenaccompaniedbyshakingchills.Afterafewdays,fevermayabateandrecrudesce,givingrisetoa“saddleback”fevercurve.Arthralgiaispolyarticular,favoringthesmalljointsandsitesofpreviousinjuries,andismostintenseonarising.Patientstypicallyavoidmovementasmuchaspossible.Jointsmayswellwithoutsignificantfluidaccumulations.Thesesymptomsmaylastfrom1weektoseveralmonthsandareaccompaniedbymyalgia.Therashcharacteristicallyappearsonthefirstdayofillness,butonsetmaybedelayed.Itusuallyarisesasaflushoverthefaceandneck,whichevolvestoamaculopapularormacularformthatmaybepruritic.Thelatterlesionsappearonthetrunk,limbs,face,plamsandsoles,inthatorderoffrequency.Petechialskinlesionshavealsobeennoted.Headache,photophobia,retro-orbitralpain,sorethroatwithobjectivesignsofpharyngitis,nauseaandvomitingalsooccurinthissetting.Occasionally,howeverpersistentarthralgiaandpolyarthritis(lastingmonthsorevenyears)dooccur,sometimesinvolvingjointdestruction.Evenrarer,sequelaeincludeencephalitisandmeningoencephalitiswithhighlethalityrates.
ThevirushasmajorimportanceinAfricaandAsia.From20%tomorethan90%ofthepopulationoftropicalandsubtropicalshowSEROlogicevidenceofinfection.BecauseAedesmosquitoesareincreasinglyprevalentinNorthAfricaandSouthAmerica,wherethepopulationwouldbeuniformlysusceptibletoinfection,thepossibilityforepidemicsisevident.ChikungunyavirusinfectionsareimportedtocentralEuropemainlybytravellerstotropicalandsubtropicalcountries.
Thepresenceofvirusresp.infectionmaybeidentifiedby
•Serology:DetectionofantibodiesbyIF,ELISA
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