IBL/IL-1α(IL-1a)ELISA/BE51001/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x2h,1x1h,1x10min |
Standardrange | 1.6-100pg/mL |
Specimen/Volumes | 50µLserum,plasma,urine,cellculturesupernatant |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | EU:CE |
Detailsfor: Interleukin-1alpha(IL-1a)ELISA
Theinterleukin-1(IL-1)speciesrepresentanimportantfamilyofBIOLOGicallyactivemononuclearcell-derivedproteinswhichareinvolvedininflammatoryreactionsandinimmuneresponses.TwodistincthumanIL-1species,IL-1alphaandIL-1beta,havebeenidentified.Theysharesimilaritiessuchasthesamemolecularweight,similarbiologicaleffectsandthesamereceptorsontargetcells.Theirbiologicalpropertiesincludepyrogenicity,boneresorption,presentationofantigentoTcellsandstimulationofBandTlymphocyteproliferation.ElevatedserumorbloodlevelsofIL-1alphahavebeenfoundinpatientswithtotalhipreplacement/arthroplasties,inpatientswithrecentlydiagnostedIDDM,incaseofseveralcarcinomassuchasheadandneckcancer,pancreaticcancerandthyroidcancer,inexperimentalacutepyelonephritis,inacuteviralhepatitisandinsepticshock.Bothelevationsinserumlevelsandjointfluids(synovialfluids)aredetectedinrheumatoidarthritis.IL-1alphaelevationisaMarkerfordentaldiseasessuchaspulpalinflammationandinfectionsoftherootcanals.Significantlyelevatedconcentrationsingingivalcrevicularfluidinsubjectswithperidantitisaredetected.UrinarylevelsofIL-1alphacorrespondtodiseaseandtherapyresponseinbladdercancer.
Synonyms:Hematopoietin-1
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Synonyms:Hematopoietin-1
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