肠内IBL/VIP血管活性物质。肽RIA/MI12021/
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商品介绍
| Kitsize | 100 |
| Method | RIA(DAb) |
| Incubationtime | 2x24h,1x30min |
| Standardrange | 3.8-120pmol/L |
| Specimen/Volumes | 200µLplasma |
| Substrate/isotope | 125-I<56kBq |
| RegulatoryStatus: | EU:CE |
Detailsfor:VIPVasoaktivesintestin.PeptidRIA
Vasoactiveintestinalpeptide(VIP)isalinearpolypeptidecontaining28aminoacidresidues.Themolecularweightis3381.VIPisstructurallyrelatedtosecretinandtoothermembersofthesecretinfamily.ThecarboxyterminalaminoacidofVIP(Asn)isamidated.ImmunocytochemicalstudieshaveshownthatVIPispresentinneuronsthroughoutthegastrointestinaltract,thecentrolandperipheralnervoussystems,thesalivaryglandsandthepancreas.VIPstimulateswaterandbicarbonatesecretionbythepancreas.VIPpossessesthecapacitytorelaxsmoothmuscle.AdmiNISTrationofVIPproducesvasodilationandpulmonarybronchodilationandrelaxesthelowereosophagaealsphincterandsmoothmuscleofthefundusofthestomach.VIPisbelievedtoplaycrucialrolesintheregulationofintestinalmotilityandintestinalepithelialionandwatertransport.IncreasedplasmaimmunoreactiveVIPconcentrationshavebeenreportedinpatientswiththeWDHAsyndrome(water,diarrhoea,hypokalemiaandachlorhydria).IncreasedplasmalevelsofVIPhavealsobeenreportedinpatientswithcirrhosis
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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