IBL/Pankreatiches多肽RIA/MI11131/
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3392242852
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4000-520-616
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商品介绍
| Kitsize | 100 |
| Method | RIA(DAb) |
| Incubationtime | 2x24h,1x1h |
| Standardrange | 6.25-200pmol/L |
| Specimen/Volumes | 100µLserum |
| Substrate/isotope | 125I<28kBq |
| RegulatoryStatus: | EU:CE |
Detailsfor:PankreatischesPolypeptidRIA
Pancreaticpolypeptide(PP)issynthesizedasanamino-terminalmoietyofaprecursorpeptide.PPisolatedfrompancreashas36aminoacidresidueswithanamidatedC-terminaltyrosine.PPissecretedbyF-cellsoftheisletsofLangerhans.PPislocalizedalmostentirelyinthepancreasalthoughdetectablelevelsthroughoutgastrointestinaltracthavebeenreported.PPinhumanplasmaisreportedtoexistinatleastfourdifferentforms:PP1-36,PP3-36andtwounidentifiedforms.PPisreleasedintoplasmaduringstimulationofmeal.ThephysiologicalroleofPPincludesinhibitionofstimulatedgastricandpancreaticexocrinesecretionsandaugmentationofinsulininhibitedhepaticglucoseproduction.TheseactionsofPParemediatedbyspecificreceptors.ReceptorbindingstudieshaveshownthattheintactC-terminaltyrosineamideisnecessaryforBIOLOGicalactivity.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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