IBL/Leptin高灵敏度ELISA/JP27775/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x1h,2x30min |
Standardrange | 15.63-1000pg/mL |
Specimen/Volumes | 100µLserum,EDTA-plasma,culturemedium |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | Forresearchuseonly |
Detailsfor: LeptinhighsensitiveELISA
Therecessiveobesitymutation,ob,identifiedin1950,resultsinprofoundobesityandtypeIIdiabetesaspartofasyndromethatresemblesmorbidobesityinhumans.Freidman’sgroupattheRockefellerUniversityoriginallyidentifiedtheobesitygenethatencodesforLeptinin1994.Leptinisa16kDasecretedproteinproducedbytheob
gene.ADIposetissueproducesLeptinandreleasesitintothebloodstream.Asfatdepositsgrow,bloodLeptinlevelstendtoincrease.IthasbeensuggestedthatLeptinactsasalipostat,increasingasfatgetsdepositedintoadipocytes.Ithasalsobeenfoundthattheproteinactsasahormoneinstructingthebraintostopfoodconsumptionandtoincreaseactivity.FurThermore,ithasbeenshowntosignalandprobablycontroltheonsetofpuberty.Inaddition,arecentstudyshowsthatLeptinmightactasapotentinhibitorofboneformationthroughcentralnervoussystem.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.gene.ADIposetissueproducesLeptinandreleasesitintothebloodstream.Asfatdepositsgrow,bloodLeptinlevelstendtoincrease.IthasbeensuggestedthatLeptinactsasalipostat,increasingasfatgetsdepositedintoadipocytes.Ithasalsobeenfoundthattheproteinactsasahormoneinstructingthebraintostopfoodconsumptionandtoincreaseactivity.FurThermore,ithasbeenshowntosignalandprobablycontroltheonsetofpuberty.Inaddition,arecentstudyshowsthatLeptinmightactasapotentinhibitorofboneformationthroughcentralnervoussystem.
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