IBL/胰岛素ELISA/RE53171/
市场价：
¥6220.00
美元价：
3732.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 2x30min,1x15min |
| Standardrange | 6.25-100µlU/mL |
| Specimen/Volumes | 25µLserum,plasma(salivaforresearch) |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Detailsfor:InsulinELISA
InsulinistheprincipalhormoneresponsIBLeforthecontrolofglucosemetabolism.Itissynthesizedintheß-cellsoftheisletsofLangerhansastheprecursor,proinsulin,whichisprocessedtoformC-peptideandinsulin.Botharesecretedinequimolaramountsintotheportalcirculation.Thematureinsulinmoleculecomprisestwopolypeptidechains,theAchainandBchain(21and30aminoacidsrespectively).Thetwochainsarelinkedtogetherbytwointer-chaindisulphidebridges.Thereisalsoanintra-chaindisulphidebridgeintheAchain.Secretionofinsulinismainlycontrolledbyplasmaglucoseconcentration,andthehormonehasanumberofimportantmetabolicactions.Itsprincipalfunctionistocontroltheuptakeandutilisationofglucoseinperipheraltissuesviatheglucosetransporter.Thisandotherhypoglycaemicactivities,suchastheinhibitionofhepaticgluconeogenesisandglycogenolysisarecounteractedbythehyperglycaemichormonesincludingglucagon,epinephrine(adrenaline),growthhormoneandcortisol.Insulinconcentrationsareseverelyreducedininsulin-dependentdiabetesmellitus(IDDM)andsomeotherconditionssuchashypopituitarism.Insulinlevelsareraisedinnon-insulin-dependentdiabetesmellitus(NIDDM),obesity,insulinomaandsomeendocrinedysfunctionssuchasCushing’ssyndromeandacromegaly.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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