IBL/GLP-1（7-36/37）活性形式HS-ELISA/30106821/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x18h,1x1h,1x30min. |
| Standardrange | 0.25-16pmol/L |
| Specimen/Volumes | 10µLrat,mouseand50µLhumanplasma |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:GLP-1(7-36/37)activeformsHSELISA
Originalarticle#27600
GLP-1(GlucagonLikePeptide-1)isatranscriptionalproductofproglucagongeneasisglucagonanditisagastrointestinalhormonesecretedfromLcellsoflowersectionofthesmallintestine.GLP-1(7-36)amideandGLP-1(7-37)areactiveformsandthesepeptidesarecleavedinbloodbyDPP4(dipeptidylpeptidase-4)intoGLP-1(9-36)amideandGLP-1(9-37)andthesepeptidesloseitsactivitiesinaveryshortperiod.GLP-1isknownasanincretinasisGIP(Glucose-dependentInsulinotropicPolypeptide).ItpromotessecretionofinsulinfromβcellsoftheisletsofLangerhansinthepancreas.GLP-1alsosuppressessecretionofglucagonfromαcellsofthepancreasandtheconcentrationofglucoseinbloodaftermeal.Drugstotreattype2diabeteshavebeendevelopedbyutilizingthefunctionalmechanismofGLP-1suchasbloodsugarcontrolthroughpancreas,delayedgastricemptyingandappetitesuppressionwhichcontributesweightlossasextra-pancreaticeffects. ThisELISAkitcanquantitativelyandspecificallymeasureGLP-1,activeform(GLP-1(7-36)amideandGLP-1(7-37)).
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.GLP-1(GlucagonLikePeptide-1)isatranscriptionalproductofproglucagongeneasisglucagonanditisagastrointestinalhormonesecretedfromLcellsoflowersectionofthesmallintestine.GLP-1(7-36)amideandGLP-1(7-37)areactiveformsandthesepeptidesarecleavedinbloodbyDPP4(dipeptidylpeptidase-4)intoGLP-1(9-36)amideandGLP-1(9-37)andthesepeptidesloseitsactivitiesinaveryshortperiod.GLP-1isknownasanincretinasisGIP(Glucose-dependentInsulinotropicPolypeptide).ItpromotessecretionofinsulinfromβcellsoftheisletsofLangerhansinthepancreas.GLP-1alsosuppressessecretionofglucagonfromαcellsofthepancreasandtheconcentrationofglucoseinbloodaftermeal.Drugstotreattype2diabeteshavebeendevelopedbyutilizingthefunctionalmechanismofGLP-1suchasbloodsugarcontrolthroughpancreas,delayedgastricemptyingandappetitesuppressionwhichcontributesweightlossasextra-pancreaticeffects. ThisELISAkitcanquantitativelyandspecificallymeasureGLP-1,activeform(GLP-1(7-36)amideandGLP-1(7-37)).
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