IBL/GLP-1（7-36），活性ELISA/RE53121/
市场价：
¥11460.00
美元价：
6876.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x20-24h,1x20min |
| Standardrange | 0.64-48pmol/L |
| Specimen/Volumes | 100µLserum,EDTA-plasma |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:GLP-1(7-36),activeELISA
IncretinsareagroupofgastrointestinalhormonesthatcauseanincreaseintheamountofinsulinreleasedfromthebetacellsoftheisletsofLangerhansaftereating.TheyalsoinhibitglucagonreleasefromthealphacellsoftheisletsofLangerhans.Asaresult,theyslowtherateofabsorptionofnutrientsintothebloodstreambyreducinggastricemptyingandmaydirectlyreducefoodintake.Thetwomaincandidatemoleculesthatfulfillcriteriaforanincretinareglucagon-likepeptide-1(GLP-1)andGastricinhibitorypeptide(orglucose-dependentinsulinotropicpolypeptideorGIP).Thehumanproglucagongenewasclonedin1983,andthehumanproglucagonsequencewassubsequentlydeduced.Afterthat,itwasfoundthatthespecificsequenceofGLP-1hasinsulinotropiceffect:GLP-1(7-36)amide.Now,GLP-1(7-36)amideandGLP-1(7-37)areknownasactiveformsofGLP-1.TheyarerapidlyinactivatedtoGLP-1(9-36)amideandGLP-1(9-37)byDPP-IVwithinafewmomentsinblood.Currently,SeveralDPP-IVinhibitorsthatcanbetakenorallyasatablethavealreadybeendevelopedasatreatmentfordiabetes.ThisELISAkitcanmeasureactiveformsofGLP-1(GLP-1(7-36)amideandGLP-1(7-37))specifically.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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