IBL/GIP活性高灵敏度(大鼠)ELISA/3011605/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x18h,1x1h,1x30min. |
Standardrange | 0.14-8.80pmol/L |
Specimen/Volumes | 10µLplasma |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | Forresearchuseonly |
Detailsfor: GIPactiveHighSensitive(rat)ELISA
Originalarticle#27704
Incretinsareagroupofgastrointestinalhormonesthatcauseanincreaseintheamountofinsulinreleasedfrombetacellsofthepancreaticisletsafterfoodintakeandtheyalsoinhibitglucagonreleasefromthealphacellsofpancreaticislets.GIP,anothertypicalincretinlikeGLP-1,wasisolatedandsequencedfromintestinalmucosaas“gastricinhibitorypeptide”in1970,andthenitwasrenamedas“glucose-dependentinsulinotropicpeptide”.IthasbeenshownthatGIPreceptorisexpressedincellssuchaspancreaticbetacells,ADIpocytesorosteoblasticcells,anditplaysessentialrolesinretainingingestednutrientswithinthebodyineachcell,andthecontrolofGIPsignalingcanleadtoimprovementofmetabolicsyndrome.ItisrapidlyinactivatedtoGIP(3-42)fromactiveformofGIP(1-42)byDPP-IVinblood.ThisELISAkitcanmeasureonlyactiveformofRatGIP(1-42).
Separatecontrolsetavailableonrequest
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Incretinsareagroupofgastrointestinalhormonesthatcauseanincreaseintheamountofinsulinreleasedfrombetacellsofthepancreaticisletsafterfoodintakeandtheyalsoinhibitglucagonreleasefromthealphacellsofpancreaticislets.GIP,anothertypicalincretinlikeGLP-1,wasisolatedandsequencedfromintestinalmucosaas“gastricinhibitorypeptide”in1970,andthenitwasrenamedas“glucose-dependentinsulinotropicpeptide”.IthasbeenshownthatGIPreceptorisexpressedincellssuchaspancreaticbetacells,ADIpocytesorosteoblasticcells,anditplaysessentialrolesinretainingingestednutrientswithinthebodyineachcell,andthecontrolofGIPsignalingcanleadtoimprovementofmetabolicsyndrome.ItisrapidlyinactivatedtoGIP(3-42)fromactiveformofGIP(1-42)byDPP-IVinblood.ThisELISAkitcanmeasureonlyactiveformofRatGIP(1-42).
Separatecontrolsetavailableonrequest
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