IBL/骨钙素放射免疫分析/MG11071/
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商品介绍
| Kitsize | 96 |
| Method | IRMA(CT) |
| Incubationtime | 1x2h |
| Standardrange | 1.9-69ng/mL |
| Specimen/Volumes | 50µLserum,plasma |
| Substrate/isotope | 125I<440kBq |
| RegulatoryStatus: | EU:CE |
Detailsfor:OsteocalcinRadioimmunoassay
Immunoradiometricassaykitfortheinvitroquantitativemeasurementofhumanintactosteocalcin(OST)inserumandplasma.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.BIOLOGicalactivities
OsteocalcinorboneGlaprotein(B.G.P)isthemajornon-collagenproteinofthebonematrix.Ithasamolecularweightof5800Daandcontains49aminoacids,including3residuesofgammacarboxylglutamicacid.Osteocalcinissynthesizedinthebonebytheosteoblasts.Afterproduction,itispartlyincorporatedinthebonematrixandtherestisfoundinthebloodcirculation.Theexactphysiologicalfunctionofosteocalcinisstillunclear.Alargenumberofstudiesshowthatthecirculatinglevelsofosteocalcinreflecttherateofboneformation.
Clinicalapplication
Thedeterminationofthebloodlevelsofosteocalcinisvaluablefor:
- Theidentificationofwomenatriskofdevelopingosteoporosis
- Monitoringbonemetabolismduringtheperimenopauseandpostmenopause
- MonitoringbonemetabolismduringhormonereplacementtherapyandtreatmentofpremenopausalwomenwithLH-RHagoNISTs
- Monitoringbonemetabolisminpatientswithgrowthhormonedeficiency,hypothyroidism,hyperthyroidism,chronicrenalfailure
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