IBL/雌三醇唾液ELISA/RE52291/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x1h,1x15min |
Standardrange | 2.5-4000pg/mL |
Specimen/Volumes | 50µLSaliva/withoutextraction |
Substrate/isotope | TMB,450nm |
RegulatoryStatus: | EU:CE |
Detailsfor: EstriolSalivaELISA
EnzymeimmunoassayforthequantitativedeterminationofEstriolinhumansaliva.
Estriol(alsoOestriol)isoneofthethreemainestrogensproducedbythehumanbody.Itisonlyproducedinsignificantamountsduringpregnancyasitismadebythefetus.Duringpregnancytheproductionofestrioldependsonanintactmaternal-placental-fetalunit.Fetalplacentalproductionofestriolleadstoaprogressiveriseinmaternalcirculating
levelsreachingalategestationalpeakseveralordersofmagnitudegreaterthannon-pregnantlevels.Inthematernalcirculation,estriolundergoesarapidconjugationintheliver
followedbyurinaryexcretionwithahalf-lifeofabout20minutes.Sincenormalestriolproductiondependsonanintactmaternal-placental-fetalcirculationandfunctionalfetalmetabolism,maternalestriollevelshavebeenusedtomonitorfetalstatusduringpregnancy,particularlyduringthethirdtrimester.
DHEA-Sisproducedbytheadrenalcortexofthefetus,thisisconvertedtoestriolbytheplacenta.Iflevelsareabnormallylowinapregnantwoman,thismayindicateaproblemwiththedevelopmentinthechild.Levelsofestriolinnon-pregnantwomendonotchangemuchaftermenopause,andlevelsarenotsignificantlydifferentfromlevelsinmen.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Estriol(alsoOestriol)isoneofthethreemainestrogensproducedbythehumanbody.Itisonlyproducedinsignificantamountsduringpregnancyasitismadebythefetus.Duringpregnancytheproductionofestrioldependsonanintactmaternal-placental-fetalunit.Fetalplacentalproductionofestriolleadstoaprogressiveriseinmaternalcirculating
levelsreachingalategestationalpeakseveralordersofmagnitudegreaterthannon-pregnantlevels.Inthematernalcirculation,estriolundergoesarapidconjugationintheliver
followedbyurinaryexcretionwithahalf-lifeofabout20minutes.Sincenormalestriolproductiondependsonanintactmaternal-placental-fetalcirculationandfunctionalfetalmetabolism,maternalestriollevelshavebeenusedtomonitorfetalstatusduringpregnancy,particularlyduringthethirdtrimester.
DHEA-Sisproducedbytheadrenalcortexofthefetus,thisisconvertedtoestriolbytheplacenta.Iflevelsareabnormallylowinapregnantwoman,thismayindicateaproblemwiththedevelopmentinthechild.Levelsofestriolinnon-pregnantwomendonotchangemuchaftermenopause,andlevelsarenotsignificantlydifferentfromlevelsinmen.
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