IBL/抗人CAD（2194）兔IgG/JP28141/
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3392242852
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4000-520-616
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商品介绍
| Quantity/Tests | 100µg |
| Species/Antigen | SyntheticpeptideintheCterminusofhumanCAD |
| Host | Rabbit |
| Subclass/Clone | IgG |
| Type | Polyclonal |
| Purification | Affinitypurifiedwithantigenpeptide |
| Label | No |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Anti-HumanCAD(2194)RabbitIgG
mTORisthetargetmoleculeofrapamycin(tradename:Sirolimus)inmammalsandithasbeenrecognizedasacentralmoleculeinthesignalingpathwayregulatingproliferationandcellgrowth.SinceDNAreplicationisalsoessentialforproliferation,regulationofcellgrowthandamino-acidperceptionitisalsocentrallyrelatedtomTORanddeeplyinvolvesinthebiosynthesisofnucleicacids.
CAD(carbamoylphosphatesynthetase,aspartatetranscarbamoylase,dihydroorotase)wasdiscoveredasaresultofasurveyformoleculesthatarerelatedtonucleicacidbiosynthesisinamolecularcomplexwithraptorandmLST8.CADhasanimportantroleinthepathwayofpyrimidinebiosynthesis.CADisanenzymethatcatalyzesthepyrimidinebiosynthesisanditselfisregulatedbyphosphorylationofotherproteinkinases.
mLST8bridgesbetweenCADandmTORandCADplaysaroleasasignalingmoleculeinthemTORpathwaybyacross-interactionwithmLST8.
ThisantibodyisconsideredasausefultoolforresearchinthemTORsignalingpathway,especiallyforresearchintheregulationsystemofnucleicacidbiosynthesis.
DistributedbyIBLInternational
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.CAD(carbamoylphosphatesynthetase,aspartatetranscarbamoylase,dihydroorotase)wasdiscoveredasaresultofasurveyformoleculesthatarerelatedtonucleicacidbiosynthesisinamolecularcomplexwithraptorandmLST8.CADhasanimportantroleinthepathwayofpyrimidinebiosynthesis.CADisanenzymethatcatalyzesthepyrimidinebiosynthesisanditselfisregulatedbyphosphorylationofotherproteinkinases.
mLST8bridgesbetweenCADandmTORandCADplaysaroleasasignalingmoleculeinthemTORpathwaybyacross-interactionwithmLST8.
ThisantibodyisconsideredasausefultoolforresearchinthemTORsignalingpathway,especiallyforresearchintheregulationsystemofnucleicacidbiosynthesis.
DistributedbyIBLInternational
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