IBL/Tenascin-C-Large(FNIII-C)酶联免疫吸附试验/JP27751/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
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3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x1h,2x30min |
Standardrange | 0.375-24ng/mL |
Specimen/Volumes | 100µLserum,plasma |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | Forresearchuseonly |
Detailsfor: Tenascin-CLarge(FNIII-C)ELISA
Tenascin-Cisanextracellularmatrix(ECM)glycoproteinthatiscomposedof210-400kDasubunitsconsistingoffourdomains.OnesubunithasaTAdomainattheN-terminalend,thenanepidermalgrowthfactor-likesequencedomain(EGF-likedomain),afibronectintypeIII(FNIII)repeatdomain,andafibrinogen-likedomainattheC-terminalend.ThereisanalternativelyspliceddomaininsidetheFNIIIdomain,anditgeneratesdifferentvariantsofTenascin-C.ThesubunitsformatrimerbytwistingattheN-terminalcoileddomainandformahexamerbyadisulfidebond,intissue.WhilelowmolecularweightvariantsofTenascin-Carepresentinnormaltissue,ithasbeenshownthathighmolecularvariantsofTenascin-Careexpressedinvariousdiseasedtissuesincludingcancer.
ThisELISAmeasuresTN-CwiththealternativelysplicedDomainC.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.ThisELISAmeasuresTN-CwiththealternativelysplicedDomainC.
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