IBL/sICAM-1 (monkey) ELISA/BE45711/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x1h,1x10min |
| Standardrange | 6.25-100U/mL |
| Specimen/Volumes | 25µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:sICAM-1(monkey)ELISA
IntercellularAdhesionMolecule-1(ICAM-1)isamemberoftheimmunoglobulinsupergenefamilyandfunctionsasaligandfortheLymphocyteFunction-AssociatedAntigen-1(LFA-1),analpha-beta-complexthatisamemberoftheleukocyteintegrinfamilyofcell-cellandcell-matrixreceptors.ThisfamilyconsistsoftheleukocyteadhesionglycoproteinsLFA-1whichmediateslymphocyteadhesion,Mac-1whichmediatesgranulocyteadhesionandp150,95.ICAM-1isasingle-chainglycoproteinwithapolypeptidecorethatcanbeexpressedonnon-hematopoieticcellsofmanylineagessuchasvascularendothelialcells,thymicepithelialcells,otherepithelialcellsandfibroblastsandonhematopoieticcellssuchastissuemacrophages,mitogen-stimulatedT-lymphoblasts,germinalcenterB-cellsanddendriticcellsintonsils,lymphnodesandPeyer"spatches.ICAM-1isinducIBLeonfibroblastsandendothelialcellsbyinflammatorymediatorssuchasIL-1,TNFandIFN-gammawithinfewhoursandiscorrelatedtotheinfiltrationoflymphocytesintoinflammatorylesions.ICAM-1seemstobetheinitialMarkerofinflammatoryreactionsandisexpressedpriorto,andtoagreaterextentthanisHLA-DR.TheroleofICAM-1asadiseasemarkerhasbeendemonstratedforanumberofdifferentindicationsandpathologicalsituations.
Synonyms:Intercellularadhesionmolecule1,CD54antigen
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Synonyms:Intercellularadhesionmolecule1,CD54antigen
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