IBL/Interleukin-17 / IL-17 (mouse) ELISA/BE45171/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x10min |
| Standardrange | 7.8-500pg/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Interleukin-17/IL-17(mouse)ELISA
MouseIL-17mRNAisspecificallyexpressedbyactivatedalphabetaTCR+CD2-CD8-T-cells,asmallsubsetwithapotentiallyimportantroleinimmuneregulation.IL-17inducesthesecretionofIL-6,IL-8,PGE2,MCP-1andG-CSFbyadherentcellslikefibroblasts,keratinocytes,epithelialandendothelialcells.IL-17isalsoabletoinduceICAM-1surfaceexpressionofT-cells.IL-17hasbeenshowntosupportthegrowthofhemopoieticProgenitors,ithasstimulatoryeffectsongranulopoiesisinmice.
IL-17mayaffectosteoclasticresorptionandtherebymediatebonedestructionaccompanyingsomeinflammatorydiseases.AstrocytesproduceNOwhenstimulatedbyIL-17,whichsuggestsapossIBLeroleforIL-17intheinflammatorydiseasesoftheCNS.ForcedexpressionofmurineIL-17inducesimmuneresponsesandmultiorganinflammation.
Interleukin-17isinvolvedintheregulationofhematopoiesisanditseffectsaredependentonthephysiological/pathologicalstatusoftheorganism.IL-17expressioninairwaysisupregulateduponallergenexposurelikeinallergicasthma.ItscrucialroleinT-cellactivationsuggeststhatIL-17isinvolvedinthedevelopmentofautoimmunearthritis.
Synonyms:Interleukin-17,IL-17A,CTLA8
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.IL-17mayaffectosteoclasticresorptionandtherebymediatebonedestructionaccompanyingsomeinflammatorydiseases.AstrocytesproduceNOwhenstimulatedbyIL-17,whichsuggestsapossIBLeroleforIL-17intheinflammatorydiseasesoftheCNS.ForcedexpressionofmurineIL-17inducesimmuneresponsesandmultiorganinflammation.
Interleukin-17isinvolvedintheregulationofhematopoiesisanditseffectsaredependentonthephysiological/pathologicalstatusoftheorganism.IL-17expressioninairwaysisupregulateduponallergenexposurelikeinallergicasthma.ItscrucialroleinT-cellactivationsuggeststhatIL-17isinvolvedinthedevelopmentofautoimmunearthritis.
Synonyms:Interleukin-17,IL-17A,CTLA8
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