IBL/γ干扰素（小鼠）ELISA/BE45201/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x10min |
| Standardrange | 15.6-1000pg/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Interferon-gamma(mouse)ELISA
IFN-gamma,alsocalledTypeIIinterferon,isahomodimericgycoproteincontainingapproximately21to24kDsubunits.IncontrasttoIFN-gammaandIFN-gammasynthesis,whichcanoccurinanycell,productionofIFN-gammaisafunctionofTcellsandNKcells.TypeIIIFNorIFN-gammaisalymphokinethatdisplaysnomolecularhomologywithtypeIIFN,butsharessomeimportantBIOLOGicactivities.Specifically,IFNinducesananti-viralstateandisanti-proliferative.Inaddition,IFN-gammahasseveralpropertiesrelatedtoimmunoregulation.
(1)IFN-isapotentactivatorofmononuclearphagocytes,e.g.IFN-gammastimulatestheexpressionofMac-1,augmentsendocytosisandphagocytosisbymonocytes;andactivatesmacrophagestokilltumorcellsbyreleasingreactiveoxagenintermediatesandTNF-alpha.
(2)IFN-gammainducesoraugmentstheexpressionofMHCantigensonmacrophages,TandBcellsandsometumorcelllines.
(3)OnTandBcellsIFN-promotesdifferentiation.ItenhacesproliferationofactivatedBcellsandcanactsynergisticallywithIL-2toincreaseimmunoglobulinlight-chainsynthesis.IFN-gammaisoneofthenaturalB-celldifferentiationfactors.
(4)Finally,IFN-gammaactivatesneutrophils,NKcellsandvascularendothelialcells.TheroleofIFN-gammaasadiseaseMarkerhasbeendemonstratedforanumberofdifferentpathologicalsituations.
Synonyms:Immuneinterferon,IFG
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.(1)IFN-isapotentactivatorofmononuclearphagocytes,e.g.IFN-gammastimulatestheexpressionofMac-1,augmentsendocytosisandphagocytosisbymonocytes;andactivatesmacrophagestokilltumorcellsbyreleasingreactiveoxagenintermediatesandTNF-alpha.
(2)IFN-gammainducesoraugmentstheexpressionofMHCantigensonmacrophages,TandBcellsandsometumorcelllines.
(3)OnTandBcellsIFN-promotesdifferentiation.ItenhacesproliferationofactivatedBcellsandcanactsynergisticallywithIL-2toincreaseimmunoglobulinlight-chainsynthesis.IFN-gammaisoneofthenaturalB-celldifferentiationfactors.
(4)Finally,IFN-gammaactivatesneutrophils,NKcellsandvascularendothelialcells.TheroleofIFN-gammaasadiseaseMarkerhasbeendemonstratedforanumberofdifferentpathologicalsituations.
Synonyms:Immuneinterferon,IFG
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