
IBL/CD23 ELISA/BE59171/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x2h,1x1h,1x10min |
Standardrange | 12.5-400U/mL |
Specimen/Volumes | 100µLserum,plasma,cellculturesupernatantetal. |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | EU:CE |
Detailsfor: CD23ELISA
CD23isdescribedasa45kDaproteinfoundonthesurfaceofIgMbearingBcells,eosinophils,macrophagesandsomeTandNKcells.ItisalsofoundonEBV-transformedBcells.Additionally,areleasedformhasbeendescribed.WhenfirstreleasedtheCD23moleculeis35kDa;however,thisformisquicklycleavedtoobtainthemorestable,solubleformwhichis25kDainsize.RecentlythestructureoftheCD23moleculewascharacterizedbycloningandsequencingtechniques.SolubleCD23hasbeenshowntobetheBcellgrowthfactor(BCGF).SolubleCD23isalsoreferredtoasBlast-2andasthelowaffinityIgEreceptor(FCeRII).IthasbeenspeculatedthatCD23mayup-regulateIgEsynthesisinconjunctionwithTcellpromotedinterleukin-4;however,thespecificphysiologicroleofthismoleculeisnotyetwellunderstood.ElevatedlevelsofCD23havebeenfoundinresearchstudiesofsamplesfrompeoplewithBcell-derivedChronicLymphocyticLeukemia(B-CLL),withHyperIgESyndromeandpost-BoneMarrowTransplantationsamples.CD23levelsmaybeproventorelatetodiseasecourseinHairyCellLeukemia(HCL).
Synonyms:ImmunoglobulinEreceptorlowaffinityII
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Synonyms:ImmunoglobulinEreceptorlowaffinityII
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