IBL/α2,6-唾液酸转移酶ELISA/JP27762/
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产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 1x60min,2x30min |
Standardrange | 1.09-70ng/mL |
Specimen/Volumes | 100µLserum,EDTA-plasma,cellculturesupernatant |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | Forresearchuseonly |
Detailsfor: alpha2,6-SialyltransferaseELISA
OneofthemajorenzymesinvolvedinAlzheimer"sDisease(AD)pathologyistheso-calledβ-secretase,alsoknownasBACE1.InhibitionofBACE1isthoughttobeausefuldrugtargetforthetreatmentofAD.Morerecentlyitwasdiscoveredthataspecificglycosyltransferaseinvolvedinthebiosynthesisofsugarchains,theα2,6-SialyltransferaseservesalsoasasubstrateforBACE1.Atthesametimealsothecleavagesiteontheα2,6-Sialyltransferasewasidentifiedinaratmodel.Thisassayallowsthemeasurementofhuman,ratandmouseα2,6-Sialyltransferase
Separatecontrolsetavailableonrequest
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Separatecontrolsetavailableonrequest
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