IBL/褪黑素提取柱/KEME761/
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Other_reagents
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商品介绍
Kitsize | N/A |
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Substrate/isotope | N/A |
RegulatoryStatus: | Forresearchuseonly |
Detailsfor: Melatonin-Extractioncolumns
Enzymeimmunoassayforthein-vitrodiagnosticquantitativedeterminationofmelatonininhumanserumandplasma.Thepinealgland(corpuspineale)hasbeencalledaneuroendocrinetransducerbecauseofitsimportantroleinphotoperiodism.ThemajorhormoneofthepinealglandisN-acetyl-5-methoxy-tryptamineormelatoninwhichissynthezisedfromtheaminoacidtryptophane.Melatoninhasitshighestlevelsinplasmaduringnighttime.Itscharacteristicnocturnalsurgeappearstoencodetemporalinformationsuchaslengthofnight.Regulationofthemelatoninsecretionisunderneuralcontrol.Sympatheticinnervationseemstoplayamajorroleviaitsreleaseofnoradrenaline.Alteredpatternsand/orlevelsofmelatoninsecretionhavebeenreportedtocoincidewithsleepdisorders,jetlag,depression,stress,schizophrenia,hypothalamicamenorrhea,pregnancy,anorexianervosa,someformsofcancer,immunologicaldisordersaswellascontrolofsexualmaturationduringpuberty.Mostofthecirculatingmelatoninismetabolizedintheliverto6-hydroxymelatoninandsubsequentlyto6-sulfatoxymelatoninwhichisexcretedintotheurine.Theconcentrationof6-hydroxymelatoninsulfateinurinecorrelateswellwiththetotallevelofmelatonininthebloodduringthecollectionperiod.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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