IBL/淀粉样β（1-40）CSF ELISA/RE59651/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x30min. |
| Standardrange | 188-1880pg/mL |
| Specimen/Volumes | 5µLCSF |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | EU:CE |
Detailsfor:Amyloid-beta(1-40)CSFELISA
In2010,thenumberofdementiapatientsworldwidewasestimatedat36million.Assuminganongoinglackofsufficientpreventiveandcurativetreatments,thisisexpectedtodoubleevery20years.Alzheimer’sDiseaseaccountsforroughly60-70%ofalldementiacases.Bothprevalenceandincidenceincreasewithage.Prevalenceisaround1%inthoseaged65-69,andmorethan30%inthoseaged90orolder.
ThedevelopmentoftheDiseaseischaracterizedbythreestages,asdefinedbytheUSNationalInstituteonAgingworkgroups.ApreclinicalstageofAlzheimer’sDisease,themildcognitiveimpairment(MCI)stageduetoAD,andthedementiastageduetoAD[9-11].Amyloidosisoccursasearlyasthepreclinicalstage.ThefirstcognitivedeficitscanmanifestthemselvesinMCIstage,whileinthedementiastagepatientsareunabletodoanyworkordailychores.
Theconcentrationofamyloid-beta(1-42)isthereforerecognizedasausefulbioMarker(incombinationwithotherbiomarkerssuchasTauandPhospho-Tau)indiagnosingAlzheimer’sDisease.Moreover,anumberofindependentstudies(forexample[3-5])showedtheratioofamyloid-beta(1-42)toamyloid-beta(1-40)tobeasuperiordiagnosticmarkerforAlzheimer’sDisease.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.ThedevelopmentoftheDiseaseischaracterizedbythreestages,asdefinedbytheUSNationalInstituteonAgingworkgroups.ApreclinicalstageofAlzheimer’sDisease,themildcognitiveimpairment(MCI)stageduetoAD,andthedementiastageduetoAD[9-11].Amyloidosisoccursasearlyasthepreclinicalstage.ThefirstcognitivedeficitscanmanifestthemselvesinMCIstage,whileinthedementiastagepatientsareunabletodoanyworkordailychores.
Theconcentrationofamyloid-beta(1-42)isthereforerecognizedasausefulbioMarker(incombinationwithotherbiomarkerssuchasTauandPhospho-Tau)indiagnosingAlzheimer’sDisease.Moreover,anumberofindependentstudies(forexample[3-5])showedtheratioofamyloid-beta(1-42)toamyloid-beta(1-40)tobeasuperiordiagnosticmarkerforAlzheimer’sDisease.
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