IBL/HB-EGF ELISA/JP27189/
市场价：
¥0.00
美元价：
0.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x18h,1x1h,1x30min. |
| Standardrange | 0.34-22nmol/L |
| Specimen/Volumes | 100µLdilutedEDTA-plasma,Serum,Urine,CSF,Cellculturesupernatant |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:HB-EGFELISA
HB-EGF(Heparin-bindingEGF-likegrowthfactor)isagrowthfactorbelongingtotheEGFfamily.ItisaligandforreceptortyrosinekinasestheErbBfamily,suchasEGFreceptor,ErbB2andErbB4.(Pro)HB-EGFiscleavedinto3differentforms:thetransmembraneformProheparin-bindingEGF-liekGrowthFactor(proHB-EGF),asolubleformofHB-EGF(sHB-EGF),whichhasbeencleavedbyproteasesatthecellsurfaceandaCterminalfragment(HB-EGF-CTF),whichremainsinthecellmembraneaftercleavage.Alltheseformsof(Pro)HB-EGFhavedifferentphysiologicalactivities.HB-EGFisexpressedinvariouscelltypessuchasepidermalcells,cardiacmyocytes,vascularendothelialcells,smoothmusclemyocytesandmacrophages.SecretedHB-EGFinbloodisinvolvedincellproliferation,differentiationandinflammatoryreactions.Besideshavingimportantrolesincellgrowth,migrationandproliferationitisalsoknownasadiphteriatoxinreceptor.
Inrecentyears,ithasattractedattentionasadrugtargetasithasbeenshownthatover-expressionofHB-EGFisessentialforcancerinvasionandmetastasis.ThisELISAmeasureshumanHB-EGFformcontainingthepropeptide.
Thisproductisforresearchuseonlyandnotforclinicaldiagnosticprocedures.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Inrecentyears,ithasattractedattentionasadrugtargetasithasbeenshownthatover-expressionofHB-EGFisessentialforcancerinvasionandmetastasis.ThisELISAmeasureshumanHB-EGFformcontainingthepropeptide.
Thisproductisforresearchuseonlyandnotforclinicaldiagnosticprocedures.
品牌介绍
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