IBL/酰化Ghrelin（猪）ELISA/CMA05401/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x16-20hat4°C,1xatRT |
| Standardrange | 3.9-500pg/mL |
| Specimen/Volumes | 100µL |
| Substrate/isotope | ER405-414nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:AcylatedGhrelin(pig)ELISA
ThisassayhasbeenvalidatedtomeasureAcylatedGhrelininbufferandinpigplasmasamples.Ghrelindiscoveredin1999,isfastbecominganendocrinologytargetofthemillennium.Ghrelin,identifiedinratstomachasanendogenousligandfortheGHsecretagoguereceptor,ismainlyproducedinstomach,buthasbeendemonstratedinmanyotherorgans.InadditiontoGH-releasingpropertiesanditsorexantaction,Ghrelincouldactasanhormonehavingeffectsongastricmotility(similaritywiththepeptidehormonemotilin),acidicsecretion,cardiovascularaction,antiproliferativeeffects,pancreaticandglucosemetabolismfunction,sleep...GhrelingeneraisestomRNAprepro-ghrelinof117aminoacids.ThisprecursorisprocessedintoGhrelin,28aminoacids(human).Beforebeingsecreted,thispeptideisoctanoylatedatSer3byGOAT(GhrelinOctanoylAcylTransferase).ThisstepisessentialforBIOLOGicalactivitymakingGOATaperfecttargetfordrugsinfeedingbehaviour.Interestingly,thepotentialtherapeuticimportanceofthishormoneisnotrestrictedtoregulationoffoodintakebutalsoincachexia(relatedtocancertreatment,anorexianervosaorischemia)gastricmotilityandmaybeinvolvedinosteoporosis,somatopause,infertilityandovulationinduction,neurologicaldisorders(Alcoholism,PostTraumaticStressdisorders...)andcardiovasculardiseases.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.品牌介绍
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