IBL/25羟基维生素D总放射免疫分析/MG11051/
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商品介绍
| Kitsize | 96 |
| Method | RIA(CT) |
| Incubationtime | 1x2h,1x1h |
| Standardrange | 10-100ng/mL |
| Specimen/Volumes | 25µLserum |
| Substrate/isotope | 125I<160kBq |
| RegulatoryStatus: | EU:CE |
Detailsfor:25-Hydroxy-VitaminDtotalRadioimmunoassay
VitaminDisthecommontermtodescribeergocalciferol,betterknownasVitaminD2,andcholecalciferol,betterknownasvitaminD3.Naturally,humansproduceVitaminD3byskinexposuretoUVsunrays.ThemainsourceforVitaminD2arefoodsanddietarysupplementations.
IntheliverthenVitaminD2andD3aremetabolisedinto25-hydroxy-VitaminD2andD3respectively.The25-Hydroxy-VitaminDisthemaincirculatingvitaminDforminthebody.
the25-hydroxy-VitaminDistheprecursorforotherVitaminDmetabolites,whichhavethenBIOLOGicalactivity.25OHD2andD3haveratherlimitedactivitybyitself.Yet,astheyaresimilarlymetabolised,theybothcontributetotheoverallVitaminDstatusofanyindividual.
Thereforeitisimportanttomeasurebothformsof25OH-VitaminDequallyforacorrectdiagnosisofVitaminDdeficiency,insufficiencyorintoxication.
VitaminDdeficiencyisanimportantriskfactorforrickets,osteomalacia,senileosteoporosis,cancerandpregnancyoutcome.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.IntheliverthenVitaminD2andD3aremetabolisedinto25-hydroxy-VitaminD2andD3respectively.The25-Hydroxy-VitaminDisthemaincirculatingvitaminDforminthebody.
the25-hydroxy-VitaminDistheprecursorforotherVitaminDmetabolites,whichhavethenBIOLOGicalactivity.25OHD2andD3haveratherlimitedactivitybyitself.Yet,astheyaresimilarlymetabolised,theybothcontributetotheoverallVitaminDstatusofanyindividual.
Thereforeitisimportanttomeasurebothformsof25OH-VitaminDequallyforacorrectdiagnosisofVitaminDdeficiency,insufficiencyorintoxication.
VitaminDdeficiencyisanimportantriskfactorforrickets,osteomalacia,senileosteoporosis,cancerandpregnancyoutcome.
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