IBL/CD40L高灵敏度ELISA/BE58941/
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产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x10min. |
| Standardrange | 0.08-5ng/ml |
| Specimen/Volumes | 20µlserum,50µlplasma |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:CD40LHighSensitivityELISA
ThisHighSensitivityELISAenablestheanalysisofTNF-alphainlowconcentrationsfromserum,plasma,orcellculturesamples.TheHighSensitivityELISAKitsofferaccuratequantificationbelowconventionalELISAlimits.
CD40belongstotheTNFreceptorsuperfamilyandisabiochemicalMarkerfortheidentificationofactivatedplateletsofpatientswithcardiovasculardiseases(anginapectoris,infarction,strokeetc.)
AkeyroleofCD40/CD40ligandinteractionsinimmuneactivation,particularlyinT-celldependentBcellresponsesisanticipated.CD40LigandisexpressedonthesurfaceofactivatedCD4+Tcells,basophils,andmastcells.BindingofCD40Ltoitsreceptor,CD40,onthesurfaceofBcellsstimulatesB-cellproliferation,adhesionanddifferentiation.AsolubleisoformofCD40Lhasbeenshowntoexistinthecirculation.Thissolublemoleculeisahomotrimerofa18kDaproteinexhibitingfullactivityinBcellproliferationanddifferentiationassays,isabletorescueBcellsfromapoptosisandbindssolubleCD40.
CD40LisdiscussedinrelationtoapotentialroleinsupportingBcelltumorsandithasbeendiscoveredthatthemoleculardefectintheX-linkedHyper-IgM-SyndromeistargetedtotheCD40Lgene,itisfunctionalinvolvedinBcellhybridomasandchroniclymphocyticleukemiaaswellasseveralautoimmunediseases.
Synonyms:CD40Ligand;TNFligandsuperfamilymember5;TNFrelatedactivationprotein;TcellantigenGp39;CD154antigen;hyperIgMsyndrome
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.CD40belongstotheTNFreceptorsuperfamilyandisabiochemicalMarkerfortheidentificationofactivatedplateletsofpatientswithcardiovasculardiseases(anginapectoris,infarction,strokeetc.)
AkeyroleofCD40/CD40ligandinteractionsinimmuneactivation,particularlyinT-celldependentBcellresponsesisanticipated.CD40LigandisexpressedonthesurfaceofactivatedCD4+Tcells,basophils,andmastcells.BindingofCD40Ltoitsreceptor,CD40,onthesurfaceofBcellsstimulatesB-cellproliferation,adhesionanddifferentiation.AsolubleisoformofCD40Lhasbeenshowntoexistinthecirculation.Thissolublemoleculeisahomotrimerofa18kDaproteinexhibitingfullactivityinBcellproliferationanddifferentiationassays,isabletorescueBcellsfromapoptosisandbindssolubleCD40.
CD40LisdiscussedinrelationtoapotentialroleinsupportingBcelltumorsandithasbeendiscoveredthatthemoleculardefectintheX-linkedHyper-IgM-SyndromeistargetedtotheCD40Lgene,itisfunctionalinvolvedinBcellhybridomasandchroniclymphocyticleukemiaaswellasseveralautoimmunediseases.
Synonyms:CD40Ligand;TNFligandsuperfamilymember5;TNFrelatedactivationprotein;TcellantigenGp39;CD154antigen;hyperIgMsyndrome
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