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当前位置: 首页 > 产品中心 > Sandwich_method_ELISA > IBL/MMP-9(基质金属蛋白酶-9)ELISA/BE59491/
商品详细IBL/MMP-9(基质金属蛋白酶-9)ELISA/BE59491/
IBL/MMP-9(基质金属蛋白酶-9)ELISA/BE59491/
IBL/MMP-9(基质金属蛋白酶-9)ELISA/BE59491/
商品编号: BE59491
品牌: TECAN
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Kitsize12x8
MethodELISA
Incubationtime1x2h;1x1h;1x10min.
Standardrange0.23-15ng/mL
Specimen/Volumes10µLserum,plasma,cellculturesupernatantetal.
Substrate/isotopeTMB450nm
RegulatoryStatus:EU:CE
Detailsfor: MMP-9(MatrixMetalloprotease-9)ELISA
MMP-9isaZn+2dependentendopeptidase,synthesizedandsecretedinmonomericformaszymogen.ThestructureisalmostsimilartoMMP2,anothermemberofmatrixmetalloproteinasefamily.

Likeotherproteolyticenzymes,MMP-9isfirstsynthesizedasinactiveproenzymeorzymogens.ActivationofproMMP-9ismediatedbyplasminogenactivator/plasmin(PA/plasmin)system.TheregulationofMMP-9activityisalsocontrolledthroughTIMP-3.

MMP-9playsanimportantroleintumorinvasion,angiogenesisandmetastasis.IncreasedlevelsofMMP-9havebeendemonstratedincolorectalcancer,inacuteleukemia,breastcancer,humanmelanomaandbladdercancer.MMP-9potentiatespulmonarymetastasisformationandgliomainvasion.Apartfromitsfunctionintumorformationandspread,MMP-9withitsdestructiveeffectsisincloseassociationwithlungdiseasesandasthma.LeukocyterecruitmenttothecentralnervoussystemMMP-9meansaninvolvementinthepathogenesisofmultiplesclerosis.MMP-9hasacrucialroleinreproductiveendocrinologyandshowsachangedexpressionpatternaftermyocardialinfarction.

Synonyms:92kDagelatinase,GelatinaseB,GELB
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
品牌介绍
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