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当前位置: 首页 > 产品中心 > Sandwich_method_ELISA > IBL/白细胞介素-10(IL-10)高灵敏度ELISA/BE58101/
商品详细IBL/白细胞介素-10(IL-10)高灵敏度ELISA/BE58101/
IBL/白细胞介素-10(IL-10)高灵敏度ELISA/BE58101/
IBL/白细胞介素-10(IL-10)高灵敏度ELISA/BE58101/
商品编号: BE58101
品牌: TECAN
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Kitsize12x8
MethodELISA
Incubationtime1x2h,1x1h,1x15min,1x30min,1x10-20min
Standardrange0.39-25pg/ml
Specimen/Volumes50µlserum,plasma,cellculturesupernatants
Substrate/isotopeTMB450nm
RegulatoryStatus:Forresearchuseonly
Detailsfor: Interleukin-10(IL-10)HighSensitivityELISA
ThisHighSensitivityELISAenablestheanalysisofInterleukin-10inlowconcentrationsfromserum,plasma,orcellculturesamples.TheHighSensitivityELISAKitsofferaccuratequantificationbelowconventionalELISAlimits.ThisismadepossIBLebytheirinherentdesignbyamplifyingthesignal.
Interleukin-10isapleiotropiccytokineplayinganimportantroleasaregulatoroflymphoidandmyeloidcellfunction.InhumansIL-10isproducedbyactivatedCD8(+)peripheralbloodT-cells,byT-helperCD4(+)T-cellclones.DuetotheABIlityofIL-10toblockcytokinesynthesisandseveralaccessorycellfunctionsofmacrophagesthiscytokineisapotentsuppressoroftheeffectorfunctionsofmacrophages,T-cellsandNKcells.Inaddition,IL-10participatesinregulatingproliferationanddifferentiationofB-cells,mastcellsandthymocytes.Basedonitsprimarystructure,IL-10isamemberofthefoura-helixbundlefamilyofcytokines.InsolutionhumanIL-10isahomodimerwithanapparentmolecularmassof39kDa.AlthoughitcontainsanN-linked,glycosylationsite,itlacksdetectablecarbohydrates.RecombinantproteinexpressedinE.colithusretainsallknownBIOLOGicalactivities.ThehumanIL-10geneislocatedonchromosome1andispresentasasinglecopyinthegenome.ThehumanIL-10exhibitsstrongDNAandaminoacidsequencehomologytothemurineIL-10andanopenreADIngframeintheEpstein-Barrvirusgenome,BCRF1whichsharesmanyofthecellularcytokine"sbiologicalactivitiesandmaythereforeplayaroleinthehost-virusinteraction.TheimmunosuppressivepropertiesofIL-10suggestapossibleclinicaluseofIL-10insuppressingrejectionsofgraftsafterorgantransplantations.IL-10canfurThermoreexertstronganti-inflammatoryactivities.

Synonyms:Cytokinesynthesisinhibitoryfactor,CSIF
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
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