IBL/Inhibin B II. Gen. ELISA/DS52021/
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美元价：
0.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x30min,1x12min |
| Standardrange | 10-1000pg/mL |
| Specimen/Volumes | 50µlserum,plasma |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:InhibinBII.Gen.ELISA
Inhibinsareheterodimericpolypeptidehormones.Theyselectivelysuppressthesecretionofpituitaryfolliclestimulatinghormone(FSH)andalsohavelocalparacrineactionsonthegonads.Thefullyprocessedformoftheinhibinmoleculehasamolecularweightofapproximately32-36kDandconsistsofthetwodistinctchains(aandß),linkedbydisulfidebridges.Highermolecularweightforms,withprecursorformsofthea-subunit,alsooccurinfollicularfluidandserum.Inaddition,freea-subunitforms,unassociatedwithaß-subunit,andlackinginhibinbioactivity,arealsopresent.InhibinBconsistsofana-subunitandaßB-subunit.InhibinBisproducedbythesertolicellsofthetestisinthemaleandthegranulosacellsoftheovaryinthefemale.ItsprimaryroleappearstobeintheregulationofgametogenesisvianegativefeedbackontheproductionofFSH.SeveralpublishedreportsindicatetheutilityofmeasurementofInhibinBasanendocrineMarkerformonitoringthemaleandfemalegonadalfunction.TheInhibinBGenIIELISAusesthehighlycharacterizedpairofantibodiesthatspecificallyrecognizeonlythefunctionaldimericinhibinmoleculeanddoesnotmeasurethefreea-subunitformspresentinBIOLOGicalfluids.Thecurrentassaydoesnotrequiresamplepre-treatmentstepwithhydrogenperoxidetooxidizetwomethioninesintheepitopetothesulfoxideforfullimmunoreactivity
Please,notethatStandardsandControlscanbeorderedseparatelyfromIBLundertheCatalogueNumberDS52026.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Please,notethatStandardsandControlscanbeorderedseparatelyfromIBLundertheCatalogueNumberDS52026.
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